TARS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006435Biological processthreonyl-tRNA aminoacylation
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0000049Molecular functiontRNA binding
GO_0004829Molecular functionthreonine-tRNA ligase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameTARS1
Protein nameThreonyl-tRNA synthetase 1
threonine--tRNA ligase (EC 6.1.1.3) (Threonyl-tRNA synthetase)
Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1)
SynonymsTARS
DescriptionFUNCTION: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) . Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage (By similarity). .

AccessionsD6RCA5
D6RCS6
ENST00000513066.3
ENST00000626210.1
ENST00000514259.5
ENST00000508361.5
ENST00000502553.5 [P26639-1]
ENST00000627006.2
D6RJ97
ENST00000505012.5
P26639
D6R9F8
D6RBR8
D6RDJ6
ENST00000455217.6 [P26639-2]
ENST00000509731.5
Q5M7Z9
ENST00000507716.5
ENST00000265112.8 [P26639-1]
ENST00000506040.1
D6RHV7