I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| OFF-bipolar cell | 3 studies | 31% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| OFF-bipolar cell | 3 studies | 31% ± 9% |
Insufficient scRNA-seq data for expression of TACR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 83% | 69.54 | 2182 / 2642 | 4% | 0.08 | 27 / 705 |
| kidney | 85% | 37.90 | 76 / 89 | 0% | 0.01 | 4 / 901 |
| bladder | 62% | 504.00 | 13 / 21 | 2% | 0.05 | 12 / 504 |
| lung | 49% | 11.75 | 283 / 578 | 2% | 0.10 | 27 / 1155 |
| muscle | 49% | 7.63 | 393 / 803 | 0% | 0 | 0 / 0 |
| stomach | 28% | 2.93 | 102 / 359 | 1% | 0.02 | 2 / 286 |
| thymus | 26% | 2.49 | 168 / 653 | 0% | 0.00 | 2 / 605 |
| intestine | 14% | 1.72 | 138 / 966 | 0% | 0.01 | 1 / 527 |
| skin | 13% | 1.19 | 228 / 1809 | 0% | 0.12 | 2 / 472 |
| esophagus | 7% | 0.85 | 95 / 1445 | 2% | 0.03 | 3 / 183 |
| breast | 2% | 0.30 | 11 / 459 | 3% | 0.05 | 28 / 1118 |
| prostate | 4% | 1.13 | 11 / 245 | 0% | 0 | 0 / 502 |
| ovary | 4% | 0.43 | 7 / 180 | 0% | 0.00 | 1 / 430 |
| uterus | 1% | 0.04 | 1 / 170 | 2% | 0.04 | 9 / 459 |
| adrenal gland | 2% | 0.14 | 4 / 258 | 1% | 0.01 | 2 / 230 |
| liver | 1% | 0.10 | 3 / 226 | 0% | 0.00 | 1 / 406 |
| pancreas | 0% | 0.02 | 1 / 328 | 1% | 0.03 | 2 / 178 |
| blood vessel | 1% | 0.37 | 19 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
| spleen | 1% | 0.10 | 3 / 241 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0.05 | 6 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.04 | 4 / 929 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.02 | 3 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042053 | Biological process | regulation of dopamine metabolic process |
| GO_0032355 | Biological process | response to estradiol |
| GO_0042220 | Biological process | response to cocaine |
| GO_0060259 | Biological process | regulation of feeding behavior |
| GO_0045777 | Biological process | positive regulation of blood pressure |
| GO_1902093 | Biological process | positive regulation of flagellated sperm motility |
| GO_0070474 | Biological process | positive regulation of uterine smooth muscle contraction |
| GO_0010460 | Biological process | positive regulation of heart rate |
| GO_0007217 | Biological process | tachykinin receptor signaling pathway |
| GO_0097225 | Cellular component | sperm midpiece |
| GO_0032590 | Cellular component | dendrite membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0032809 | Cellular component | neuronal cell body membrane |
| GO_0004995 | Molecular function | tachykinin receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TACR3 |
| Protein name | Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3) Neuromedin-K receptor (NK-3 receptor) (Neurokinin B receptor) (Tachykinin receptor 3) |
| Synonyms | NK3R TAC3R |
| Description | FUNCTION: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. |
| Accessions | Q0IIN4 P29371 ENST00000304883.3 A0A1B0RPQ1 Q4VBL9 |
