TAC4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TAC4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TAC4 at tissue level.

III. Associated gene sets

GO_0008217Biological processregulation of blood pressure
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0006954Biological processinflammatory response
GO_1902093Biological processpositive regulation of flagellated sperm motility
GO_0007217Biological processtachykinin receptor signaling pathway
GO_0005615Cellular componentextracellular space
GO_0031835Molecular functionsubstance P receptor binding

IV. Literature review

[source]
Gene nameTAC4
Protein nameTachykinin-4 (Preprotachykinin-C) (PPT-C) [Cleaved into: Endokinin-A (EKA); Endokinin-A/B (EKA/B); Endokinin-C (EKC)]
Synonyms
DescriptionFUNCTION: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility. .

AccessionsQ86UU9
ENST00000436235.6 [Q86UU9-5]
ENST00000398154.5 [Q86UU9-2]
ENST00000326219.5 [Q86UU9-3]
ENST00000352793.6 [Q86UU9-4]
ENST00000334568.8 [Q86UU9-1]