I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 10 studies | 28% ± 10% | |
| basal cell | 5 studies | 33% ± 24% | |
| respiratory goblet cell | 4 studies | 20% ± 1% | |
| keratinocyte | 3 studies | 21% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 10 studies | 28% ± 10% | |
| basal cell | 5 studies | 33% ± 24% | |
| respiratory goblet cell | 4 studies | 20% ± 1% | |
| keratinocyte | 3 studies | 21% ± 3% |
Insufficient scRNA-seq data for expression of SYT8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 87% | 982.12 | 286 / 328 | 92% | 73.27 | 163 / 178 |
| bladder | 76% | 5631.57 | 16 / 21 | 69% | 70.87 | 346 / 504 |
| lung | 67% | 538.06 | 385 / 578 | 50% | 9.22 | 575 / 1155 |
| ureter | 0% | 0 | 0 / 0 | 100% | 53.10 | 1 / 1 |
| esophagus | 38% | 1274.07 | 552 / 1445 | 57% | 10.21 | 104 / 183 |
| breast | 44% | 785.13 | 200 / 459 | 32% | 5.22 | 363 / 1118 |
| skin | 71% | 5498.64 | 1291 / 1809 | 4% | 0.16 | 18 / 472 |
| uterus | 4% | 14.89 | 7 / 170 | 63% | 29.36 | 290 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 5.03 | 23 / 45 |
| stomach | 14% | 64.44 | 52 / 359 | 36% | 6.00 | 103 / 286 |
| intestine | 10% | 60.77 | 94 / 966 | 31% | 5.42 | 166 / 527 |
| ovary | 0% | 0 | 0 / 180 | 33% | 3.31 | 143 / 430 |
| prostate | 29% | 287.06 | 72 / 245 | 3% | 0.13 | 13 / 502 |
| liver | 3% | 14.49 | 7 / 226 | 19% | 10.32 | 79 / 406 |
| thymus | 1% | 4.38 | 5 / 653 | 5% | 0.23 | 31 / 605 |
| kidney | 0% | 0 | 0 / 89 | 6% | 1.16 | 50 / 901 |
| adrenal gland | 2% | 12.51 | 4 / 258 | 3% | 1.67 | 6 / 230 |
| blood vessel | 4% | 20.33 | 51 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 0% | 1.23 | 1 / 241 | 0% | 0 | 0 / 0 |
| muscle | 0% | 1.81 | 3 / 803 | 0% | 0 | 0 / 0 |
| adipose | 0% | 4.52 | 4 / 1204 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.18 | 1 / 2642 | 0% | 0.01 | 1 / 705 |
| heart | 0% | 0.33 | 1 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0048488 | Biological process | synaptic vesicle endocytosis |
| GO_0048791 | Biological process | calcium ion-regulated exocytosis of neurotransmitter |
| GO_0070382 | Cellular component | exocytic vesicle |
| GO_0030424 | Cellular component | axon |
| GO_0030672 | Cellular component | synaptic vesicle membrane |
| GO_0001669 | Cellular component | acrosomal vesicle |
| GO_0031045 | Cellular component | dense core granule |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030276 | Molecular function | clathrin binding |
| GO_0000149 | Molecular function | SNARE binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0001786 | Molecular function | phosphatidylserine binding |
| GO_0005544 | Molecular function | calcium-dependent phospholipid binding |
| Gene name | SYT8 |
| Protein name | Synaptotagmin 8 Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII) |
| Synonyms | |
| Description | FUNCTION: Involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of exocytosis in insulin secreted cells. . |
| Accessions | C9J253 ENST00000417052.5 C9K032 F8WBL4 ENST00000341958.4 [Q8NBV8-4] Q8NBV8 ENST00000424556.2 ENST00000381978.7 ENST00000430303.5 A0AA75HZC2 ENST00000381968.7 ENST00000673308.1 [Q8NBV8-4] H0Y3G9 |
