I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 34% ± 18% | |
| retinal ganglion cell | 4 studies | 40% ± 25% | |
| neuron | 3 studies | 21% ± 4% | |
| GABAergic neuron | 3 studies | 39% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 34% ± 18% | |
| retinal ganglion cell | 4 studies | 40% ± 25% | |
| neuron | 3 studies | 21% ± 4% | |
| GABAergic neuron | 3 studies | 39% ± 8% |
Insufficient scRNA-seq data for expression of SYNGR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 95% | 6306.93 | 2505 / 2642 | 90% | 20.32 | 631 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 11.71 | 29 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 17.23 | 40 / 45 |
| intestine | 45% | 306.07 | 430 / 966 | 42% | 3.02 | 222 / 527 |
| adrenal gland | 11% | 125.51 | 28 / 258 | 73% | 46.92 | 168 / 230 |
| ovary | 1% | 3.12 | 1 / 180 | 73% | 6.47 | 312 / 430 |
| uterus | 0% | 0 | 0 / 170 | 65% | 10.28 | 299 / 459 |
| pancreas | 0% | 0 | 0 / 328 | 62% | 3.60 | 111 / 178 |
| stomach | 8% | 50.29 | 29 / 359 | 44% | 2.76 | 127 / 286 |
| lung | 2% | 14.68 | 11 / 578 | 49% | 3.43 | 566 / 1155 |
| kidney | 19% | 101.70 | 17 / 89 | 31% | 5.95 | 282 / 901 |
| breast | 0% | 0 | 0 / 459 | 46% | 2.97 | 513 / 1118 |
| esophagus | 6% | 33.04 | 87 / 1445 | 32% | 1.67 | 58 / 183 |
| skin | 0% | 2.35 | 7 / 1809 | 32% | 2.04 | 150 / 472 |
| bladder | 0% | 0 | 0 / 21 | 31% | 2.63 | 156 / 504 |
| peripheral blood | 17% | 141.22 | 154 / 929 | 0% | 0 | 0 / 0 |
| thymus | 1% | 4.38 | 6 / 653 | 14% | 0.72 | 87 / 605 |
| liver | 0% | 0 | 0 / 226 | 12% | 1.06 | 47 / 406 |
| eye | 0% | 0 | 0 / 0 | 10% | 0.61 | 8 / 80 |
| spleen | 9% | 43.88 | 21 / 241 | 0% | 0 | 0 / 0 |
| prostate | 2% | 13.81 | 5 / 245 | 5% | 0.31 | 25 / 502 |
| heart | 0% | 0.57 | 1 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.29 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0051580 | Biological process | regulation of neurotransmitter uptake |
| GO_0045055 | Biological process | regulated exocytosis |
| GO_0032411 | Biological process | positive regulation of transporter activity |
| GO_0021762 | Biological process | substantia nigra development |
| GO_0030672 | Cellular component | synaptic vesicle membrane |
| GO_0008021 | Cellular component | synaptic vesicle |
| GO_0031594 | Cellular component | neuromuscular junction |
| GO_0016020 | Cellular component | membrane |
| GO_0042169 | Molecular function | SH2 domain binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SYNGR3 |
| Protein name | Synaptogyrin 3 Synaptogyrin-3 |
| Synonyms | |
| Description | FUNCTION: May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal. . |
| Accessions | H3BNA6 O43761 ENST00000709282.1 H3BPJ5 ENST00000568896.1 H3BQ28 ENST00000562045.1 ENST00000248121.7 ENST00000563869.1 |
