SUMO1P1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SUMO1P1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SUMO1P1 at tissue level.

III. Associated gene sets

GO_0016925Biological processprotein sumoylation
GO_0030578Biological processPML body organization
GO_0016605Cellular componentPML body
GO_0005634Cellular componentnucleus
GO_0008134Molecular functiontranscription factor binding
GO_0031386Molecular functionprotein tag activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0044389Molecular functionubiquitin-like protein ligase binding

IV. Literature review

[source]
Gene nameSUMO1P1
Protein nameSmall ubiquitin-related modifier 5 (SUMO-5) (SUMO1 pseudogene 1) (Ubiquitin-like 2) (Ubiquitin-like 6)
SynonymsSUMO5
UBL6
UBL2
DescriptionFUNCTION: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Regulates the life cycle of promyelocytic leukemia nuclear bodies (PML-NBs). PolySUMO1P1/SUMO5 conjugation on 'Lys-160' of PML facilitates recruitment of PML-NB components, which enlarges PML-NB. SUMO1P1/SUMO5 also increases polySUMO2/3 conjugation of PML, resulting in RNF4-mediated disruption of PML-NBs. .

AccessionsG2XKQ0