SULT2A1 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	5 studies	24% ± 6%	Explore
hepatocyte	4 studies	73% ± 11%	Explore

Name	Number of supported studies	Average coverage
liver	3 studies	41% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	29686.77	226 / 226	89%	651.56	362 / 406
adrenal gland	100%	21367.99	258 / 258	41%	439.14	95 / 230
bladder	67%	196.33	14 / 21	19%	10.50	98 / 504
stomach	79%	670.40	284 / 359	7%	3.67	20 / 286
intestine	29%	171.92	281 / 966	5%	1.86	28 / 527
peripheral blood	30%	69.93	281 / 929	0%	0	0 / 0
ovary	23%	12.47	42 / 180	0%	0.17	1 / 430
pancreas	18%	3.41	59 / 328	4%	0.97	8 / 178
spleen	22%	51.02	52 / 241	0%	0	0 / 0
lung	18%	4.21	102 / 578	1%	0.56	10 / 1155
esophagus	11%	3.25	153 / 1445	4%	2.45	7 / 183
uterus	13%	3.16	22 / 170	1%	0.54	6 / 459
prostate	14%	4.49	34 / 245	0%	0	0 / 502
thymus	10%	8.13	64 / 653	0%	0.02	1 / 605
adipose	10%	9.41	118 / 1204	0%	0	0 / 0
blood vessel	8%	2.11	103 / 1335	0%	0	0 / 0
skin	7%	2.02	131 / 1809	0%	0.21	2 / 472
kidney	7%	0.80	6 / 89	1%	0.88	6 / 901
breast	7%	4.08	32 / 459	0%	0.02	1 / 1118
heart	7%	2.17	59 / 861	0%	0	0 / 0
brain	6%	1.65	167 / 2642	0%	0	0 / 705
muscle	5%	0.84	38 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008203	Biological process	cholesterol metabolic process
GO_0050427	Biological process	3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO_0006805	Biological process	xenobiotic metabolic process
GO_0006068	Biological process	ethanol catabolic process
GO_0051923	Biological process	sulfation
GO_0042403	Biological process	thyroid hormone metabolic process
GO_0008202	Biological process	steroid metabolic process
GO_0030573	Biological process	bile acid catabolic process
GO_0016042	Biological process	lipid catabolic process
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0050656	Molecular function	3'-phosphoadenosine 5'-phosphosulfate binding
GO_0050294	Molecular function	steroid sulfotransferase activity
GO_0008146	Molecular function	sulfotransferase activity
GO_0005515	Molecular function	protein binding
GO_0047704	Molecular function	bile-salt sulfotransferase activity
GO_0004027	Molecular function	alcohol sulfotransferase activity

Gene name	SULT2A1
Protein name	Sulfotransferase (EC 2.8.2.-) Sulfotransferase 2A1 (ST2A1) (EC 2.8.2.2) (Bile salt sulfotransferase) (EC 2.8.2.14) (Dehydroepiandrosterone sulfotransferase) (DHEA-ST) (DHEA-ST8) (Hydroxysteroid Sulfotransferase) (HST) (ST2) (SULT2A3)
Synonyms	HST hCG_201431 STD
Description	FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups . Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis . Plays a key role in bile acid metabolism . In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols (By similarity). .
Accessions	Q06520 ENST00000222002.4 A8K015

SULT2A1 report