SULT1C3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SULT1C3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SULT1C3 at tissue level.

III. Associated gene sets

GO_0050427Biological process3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO_0006805Biological processxenobiotic metabolic process
GO_0051923Biological processsulfation
GO_0006629Biological processlipid metabolic process
GO_0005737Cellular componentcytoplasm
GO_0050656Molecular function3'-phosphoadenosine 5'-phosphosulfate binding
GO_0004062Molecular functionaryl sulfotransferase activity
GO_0005515Molecular functionprotein binding
GO_0004027Molecular functionalcohol sulfotransferase activity

IV. Literature review

[source]
Gene nameSULT1C3
Protein nameSulfotransferase 1C3 (ST1C3) (EC 2.8.2.1) (EC 2.8.2.2)
Synonyms
DescriptionFUNCTION: [Isoform 1]: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor. Has sulfotransferase activity towards various substrates, such as bile acids, thyroid hormones and toward xenobiotic compounds such as chloro phenols and hydroxypyrenes. Lithocholic acid appears to be the best substrate among the endogenous compounds tested and 3,3',5,5'-tetrachloro-4,4'-biphenyldiol shows the highest specific activity among the xenobiotic compounds. .; FUNCTION: [Isoform 2]: Exhibits weak sulphating activity and only toward chloro phenols (pentachlorophenol and 3,3',5,5'-tetrachloro-4,4'-biphenyldiol). .

AccessionsENST00000329106.3 [Q6IMI6-1]
ENST00000681802.2 [Q6IMI6-2]
Q6IMI6