SULT1C2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051923Biological processsulfation
GO_0009308Biological processamine metabolic process
GO_0005764Cellular componentlysosome
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0008146Molecular functionsulfotransferase activity
GO_0004062Molecular functionaryl sulfotransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSULT1C2
Protein nameSulfotransferase (EC 2.8.2.-)
Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.1) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2)
SynonymsSULT1C1
DescriptionFUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic compounds. Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol . Catalyzes the sulfonation of the carcinogenic N-Hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis . .

AccessionsC9JSR0
B4DLP0
ENST00000437390.6
H7C420
H7BZ17
ENST00000409067.2
ENST00000442801.5
ENST00000409880.5
ENST00000438339.5
O00338
B8ZZF7
ENST00000251481.11 [O00338-1]
ENST00000326853.9 [O00338-2]