SULT1B1 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	6 studies	27% ± 5%	Explore
epithelial cell	6 studies	24% ± 11%	Explore

Name	Number of supported studies	Average coverage
intestine	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	82%	1952.31	296 / 359	94%	20.38	268 / 286
liver	100%	2185.96	226 / 226	71%	7.16	289 / 406
intestine	66%	4088.25	641 / 966	92%	23.24	484 / 527
lung	80%	557.63	462 / 578	28%	2.92	329 / 1155
ureter	0%	0	0 / 0	100%	2.88	1 / 1
spleen	100%	1990.80	240 / 241	0%	0	0 / 0
pancreas	4%	7.95	12 / 328	81%	17.08	144 / 178
esophagus	24%	75.06	343 / 1445	60%	14.75	109 / 183
peripheral blood	80%	5813.91	745 / 929	0%	0	0 / 0
bladder	24%	48.33	5 / 21	37%	6.65	188 / 504
brain	21%	68.46	564 / 2642	25%	0.45	176 / 705
adipose	43%	178.98	514 / 1204	0%	0	0 / 0
uterus	27%	74.80	46 / 170	14%	0.77	66 / 459
tonsil	0%	0	0 / 0	38%	1.04	17 / 45
skin	29%	996.26	521 / 1809	8%	0.47	36 / 472
breast	30%	102.46	138 / 459	6%	0.53	63 / 1118
thymus	16%	37.95	106 / 653	14%	0.21	84 / 605
blood vessel	28%	89.81	369 / 1335	0%	0	0 / 0
kidney	6%	19.04	5 / 89	20%	0.52	184 / 901
prostate	24%	61.24	59 / 245	2%	0.02	8 / 502
ovary	24%	75.75	44 / 180	1%	0.03	5 / 430
lymph node	0%	0	0 / 0	21%	0.34	6 / 29
adrenal gland	13%	28.58	34 / 258	6%	0.32	14 / 230
heart	17%	40.61	149 / 861	0%	0	0 / 0
muscle	0%	0.18	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0018958	Biological process	phenol-containing compound metabolic process
GO_0050427	Biological process	3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO_0009812	Biological process	flavonoid metabolic process
GO_0006805	Biological process	xenobiotic metabolic process
GO_0006068	Biological process	ethanol catabolic process
GO_0051923	Biological process	sulfation
GO_0042403	Biological process	thyroid hormone metabolic process
GO_0006576	Biological process	biogenic amine metabolic process
GO_0030855	Biological process	epithelial cell differentiation
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0008146	Molecular function	sulfotransferase activity
GO_0004062	Molecular function	aryl sulfotransferase activity
GO_0005515	Molecular function	protein binding

Gene name	SULT1B1
Protein name	Sulfotransferase 1B1 (ST1B1) (EC 2.8.2.1) (Sulfotransferase 1B2) (Sulfotransferase family cytosolic 1B member 1) (Thyroid hormone sulfotransferase) Sulfotransferase (EC 2.8.2.-)
Synonyms	ST1B2 SULT1B2
Description	FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3) . May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system . .
Accessions	ENST00000510821.1 D6RIA8 D6RD70 ENST00000310613.8 ENST00000512870.1 O43704

SULT1B1 report