STYXL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2001242Biological processregulation of intrinsic apoptotic signaling pathway
GO_2001244Biological processpositive regulation of intrinsic apoptotic signaling pathway
GO_0062030Biological processnegative regulation of stress granule assembly
GO_0035556Biological processintracellular signal transduction
GO_0010976Biological processpositive regulation of neuron projection development
GO_0032515Biological processnegative regulation of phosphoprotein phosphatase activity
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0004864Molecular functionprotein phosphatase inhibitor activity
GO_0001691Molecular functionpseudophosphatase activity
GO_0005515Molecular functionprotein binding
GO_0019903Molecular functionprotein phosphatase binding

IV. Literature review

[source]
Gene nameSTYXL1
Protein nameSerine/threonine/tyrosine-interacting-like protein 1 (Dual specificity phosphatase inhibitor MK-STYX) (Dual specificity protein phosphatase 24) (Inactive dual specificity protein phosphatase MK-STYX) (Map kinase phosphatase-like protein MK-STYX)
Serine/threonine/tyrosine interacting like 1
SynonymsMKSTYX
DUSP24
DescriptionFUNCTION: Catalytically inactive phosphatase . By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules . Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149' . Inhibits PTPMT1 phosphatase activity . By inhibiting PTPMT1, positively regulates intrinsic apoptosis . May play a role in the formation of neurites during neuronal development . .

AccessionsA0A0C4DG63
Q9Y6J8
H0Y6C4
ENST00000360591.7 [Q9Y6J8-4]
ENST00000438695.5
ENST00000248600.5 [Q9Y6J8-1]
C9J4H0
ENST00000431581.5 [Q9Y6J8-1]
H7C1Y2
ENST00000430497.5
ENST00000359697.8 [Q9Y6J8-1]
ENST00000454618.5
ENST00000340062.9 [Q9Y6J8-4]
ENST00000451157.1