STYX | OmnibusX

Name	Number of supported studies	Average coverage
brain	3 studies	18% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	1264.56	459 / 459	100%	24.69	1118 / 1118
esophagus	100%	1384.45	1445 / 1445	100%	28.18	183 / 183
liver	100%	1754.45	226 / 226	100%	16.07	406 / 406
ovary	100%	1039.93	180 / 180	100%	13.34	430 / 430
uterus	100%	1111.41	170 / 170	100%	17.88	459 / 459
prostate	100%	1024.90	245 / 245	100%	15.80	501 / 502
bladder	100%	1288.38	21 / 21	100%	14.45	502 / 504
thymus	100%	910.81	652 / 653	100%	12.81	603 / 605
lung	99%	1030.80	575 / 578	100%	20.75	1155 / 1155
intestine	100%	1207.94	966 / 966	99%	13.75	523 / 527
kidney	100%	771.70	89 / 89	99%	13.46	891 / 901
pancreas	99%	797.93	326 / 328	99%	13.10	177 / 178
stomach	100%	1109.50	359 / 359	99%	15.28	282 / 286
brain	98%	513.13	2599 / 2642	100%	11.33	705 / 705
skin	100%	1559.65	1809 / 1809	96%	15.34	451 / 472
adrenal gland	100%	659.74	258 / 258	90%	6.75	208 / 230
adipose	100%	1415.48	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1354.26	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	18.82	29 / 29
muscle	100%	1339.38	803 / 803	0%	0	0 / 0
spleen	100%	1167.58	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	17.65	45 / 45
ureter	0%	0	0 / 0	100%	8.54	1 / 1
heart	99%	832.77	853 / 861	0%	0	0 / 0
peripheral blood	84%	882.45	782 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	73%	5.23	58 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0062026	Biological process	negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process
GO_0032091	Biological process	negative regulation of protein binding
GO_0070372	Biological process	regulation of ERK1 and ERK2 cascade
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_1990444	Molecular function	F-box domain binding
GO_0001691	Molecular function	pseudophosphatase activity
GO_0005515	Molecular function	protein binding

Gene name	STYX
Protein name	Serine/threonine/tyrosine-interacting protein (Inactive tyrosine-protein phosphatase STYX) (Phosphoserine/threonine/tyrosine interaction protein)
Synonyms
Description	FUNCTION: Catalytically inactive phosphatase . Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2) . Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2) . By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates . Plays a role in spermatogenesis (By similarity). .
Accessions	ENST00000354586.5 ENST00000442123.6 Q8WUJ0

STYX report