Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 12 studies | 75% ± 27% | |
GABAergic neuron | 11 studies | 64% ± 31% | |
oligodendrocyte precursor cell | 11 studies | 58% ± 21% | |
astrocyte | 8 studies | 36% ± 23% | |
interneuron | 6 studies | 69% ± 22% | |
retinal cone cell | 6 studies | 52% ± 28% | |
neuron | 5 studies | 45% ± 15% | |
endothelial cell | 5 studies | 47% ± 23% | |
microglial cell | 5 studies | 41% ± 21% | |
granule cell | 4 studies | 80% ± 15% | |
amacrine cell | 4 studies | 46% ± 15% | |
retina horizontal cell | 4 studies | 30% ± 10% | |
GABAergic interneuron | 3 studies | 79% ± 9% | |
GABAergic amacrine cell | 3 studies | 57% ± 20% | |
glycinergic amacrine cell | 3 studies | 51% ± 8% | |
retinal ganglion cell | 3 studies | 29% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 95% | 3562.84 | 2501 / 2642 | 75% | 4.63 | 527 / 705 |
adrenal gland | 56% | 222.40 | 145 / 258 | 73% | 3.79 | 169 / 230 |
thymus | 98% | 1075.50 | 642 / 653 | 30% | 1.57 | 183 / 605 |
prostate | 81% | 497.22 | 198 / 245 | 43% | 1.10 | 217 / 502 |
ovary | 97% | 1952.03 | 175 / 180 | 2% | 0.04 | 9 / 430 |
bladder | 57% | 396.57 | 12 / 21 | 6% | 0.42 | 32 / 504 |
uterus | 47% | 197.39 | 80 / 170 | 9% | 0.31 | 41 / 459 |
intestine | 42% | 253.58 | 401 / 966 | 3% | 0.09 | 14 / 527 |
esophagus | 4% | 10.94 | 57 / 1445 | 11% | 0.67 | 20 / 183 |
lung | 0% | 0 | 0 / 578 | 13% | 0.56 | 150 / 1155 |
pancreas | 1% | 3.23 | 4 / 328 | 10% | 0.41 | 17 / 178 |
eye | 0% | 0 | 0 / 0 | 9% | 0.17 | 7 / 80 |
skin | 0% | 0.84 | 7 / 1809 | 7% | 0.18 | 31 / 472 |
stomach | 2% | 5.45 | 8 / 359 | 5% | 0.17 | 13 / 286 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.14 | 3 / 45 |
kidney | 0% | 0 | 0 / 89 | 6% | 0.39 | 55 / 901 |
breast | 0% | 0 | 0 / 459 | 4% | 0.14 | 46 / 1118 |
blood vessel | 1% | 4.97 | 14 / 1335 | 0% | 0 | 0 / 0 |
adipose | 0% | 1.33 | 6 / 1204 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 0% | 0.02 | 2 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0015031 | Biological process | protein transport |
GO_0006887 | Biological process | exocytosis |
GO_0006893 | Biological process | Golgi to plasma membrane transport |
GO_0005737 | Cellular component | cytoplasm |
GO_0005886 | Cellular component | plasma membrane |
GO_0031201 | Cellular component | SNARE complex |
GO_0045159 | Molecular function | myosin II binding |
GO_0005515 | Molecular function | protein binding |
GO_0019905 | Molecular function | syntaxin binding |
GO_0005096 | Molecular function | GTPase activator activity |
Gene name | STXBP5L |
Protein name | Syntaxin binding protein 5L Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2) |
Synonyms | KIAA1006 LLGL4 |
Description | FUNCTION: Plays a role in vesicle trafficking and exocytosis inhibition. In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane. Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (By similarity). Promotes as well axonal outgrowth . . |
Accessions | ENST00000492541.5 C9K0E4 C9JQS3 ENST00000497029.5 ENST00000471454.6 ENST00000707001.1 [Q9Y2K9-1] E9PFI2 C9JPK3 ENST00000472879.5 ENST00000471262.1 C9JUZ7 Q9Y2K9 ENST00000273666.10 [Q9Y2K9-1] C9JCY1 ENST00000461772.5 [Q9Y2K9-2] ENST00000495504.5 |