STX17 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0097111Biological processendoplasmic reticulum-Golgi intermediate compartment organization
GO_0034497Biological processprotein localization to phagophore assembly site
GO_0006886Biological processintracellular protein transport
GO_0016240Biological processautophagosome membrane docking
GO_0007030Biological processGolgi organization
GO_0006887Biological processexocytosis
GO_0048278Biological processvesicle docking
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0006906Biological processvesicle fusion
GO_0097352Biological processautophagosome maturation
GO_0030897Cellular componentHOPS complex
GO_0005886Cellular componentplasma membrane
GO_0012505Cellular componentendomembrane system
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005739Cellular componentmitochondrion
GO_0000421Cellular componentautophagosome membrane
GO_0033116Cellular componentendoplasmic reticulum-Golgi intermediate compartment membrane
GO_0030868Cellular componentsmooth endoplasmic reticulum membrane
GO_0044233Cellular componentmitochondria-associated endoplasmic reticulum membrane contact site
GO_0005829Cellular componentcytosol
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0005776Cellular componentautophagosome
GO_0030134Cellular componentCOPII-coated ER to Golgi transport vesicle
GO_0012507Cellular componentER to Golgi transport vesicle membrane
GO_0005791Cellular componentrough endoplasmic reticulum
GO_0031201Cellular componentSNARE complex
GO_0005765Cellular componentlysosomal membrane
GO_0019903Molecular functionprotein phosphatase binding
GO_0019901Molecular functionprotein kinase binding
GO_0000149Molecular functionSNARE binding
GO_0005484Molecular functionSNAP receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSTX17
Protein nameSyntaxin 17
Syntaxin-17
STX17 protein
Synonyms
DescriptionFUNCTION: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion . STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane . May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi . .

AccessionsP56962
ENST00000525342.5
Q2TAB5
ENST00000526607.1
ENST00000529340.5
ENST00000524405.5
Q6NSC7
ENST00000525640.5
ENST00000259400.11
ENST00000531035.5
E9PQU9
E9PJW1
E9PIC2
ENST00000534052.1
E9PJV6