Name | Number of supported studies | Average coverage | |
---|---|---|---|
erythrocyte | 11 studies | 51% ± 14% | |
retinal cone cell | 6 studies | 52% ± 17% | |
erythroblast | 5 studies | 44% ± 23% | |
epithelial cell | 5 studies | 24% ± 10% | |
astrocyte | 5 studies | 27% ± 12% | |
glutamatergic neuron | 5 studies | 34% ± 15% | |
cardiac muscle cell | 4 studies | 28% ± 6% | |
GABAergic neuron | 4 studies | 35% ± 9% | |
interneuron | 4 studies | 36% ± 18% | |
oligodendrocyte | 4 studies | 23% ± 4% | |
epithelial cell of proximal tubule | 3 studies | 23% ± 5% | |
endothelial cell | 3 studies | 17% ± 1% | |
enterocyte | 3 studies | 17% ± 2% | |
neuron | 3 studies | 21% ± 3% | |
oligodendrocyte precursor cell | 3 studies | 28% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 3056.41 | 226 / 226 | 100% | 36.97 | 406 / 406 |
brain | 100% | 1488.04 | 2637 / 2642 | 100% | 48.48 | 704 / 705 |
prostate | 100% | 1047.05 | 244 / 245 | 100% | 22.49 | 501 / 502 |
kidney | 100% | 3452.28 | 89 / 89 | 99% | 30.16 | 894 / 901 |
thymus | 100% | 1283.72 | 652 / 653 | 99% | 33.21 | 600 / 605 |
adrenal gland | 100% | 4505.83 | 258 / 258 | 99% | 22.27 | 227 / 230 |
breast | 100% | 1512.41 | 459 / 459 | 99% | 19.66 | 1102 / 1118 |
esophagus | 99% | 994.32 | 1435 / 1445 | 98% | 14.13 | 180 / 183 |
ovary | 99% | 984.24 | 179 / 180 | 98% | 14.68 | 421 / 430 |
intestine | 100% | 1570.74 | 963 / 966 | 97% | 16.80 | 512 / 527 |
lung | 97% | 990.84 | 560 / 578 | 97% | 15.12 | 1126 / 1155 |
pancreas | 97% | 795.32 | 318 / 328 | 96% | 10.43 | 170 / 178 |
uterus | 100% | 1142.36 | 170 / 170 | 90% | 13.14 | 411 / 459 |
bladder | 100% | 862.62 | 21 / 21 | 89% | 12.08 | 450 / 504 |
stomach | 92% | 609.81 | 329 / 359 | 97% | 16.75 | 277 / 286 |
skin | 75% | 1029.76 | 1360 / 1809 | 100% | 39.13 | 471 / 472 |
eye | 0% | 0 | 0 / 0 | 100% | 71.04 | 80 / 80 |
muscle | 100% | 4407.68 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1086.30 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.82 | 1 / 1 |
adipose | 100% | 1507.62 | 1202 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 4765.19 | 915 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 96% | 726.50 | 1279 / 1335 | 0% | 0 | 0 / 0 |
heart | 94% | 1652.44 | 812 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 82% | 7.43 | 37 / 45 |
lymph node | 0% | 0 | 0 / 0 | 79% | 10.71 | 23 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032147 | Biological process | activation of protein kinase activity |
GO_0007254 | Biological process | JNK cascade |
GO_2001240 | Biological process | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
GO_0000902 | Biological process | cell morphogenesis |
GO_0006468 | Biological process | protein phosphorylation |
GO_0006611 | Biological process | protein export from nucleus |
GO_0005829 | Cellular component | cytosol |
GO_1902554 | Cellular component | serine/threonine protein kinase complex |
GO_0016235 | Cellular component | aggresome |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0043539 | Molecular function | protein serine/threonine kinase activator activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
GO_0004672 | Molecular function | protein kinase activity |
Gene name | STRADB |
Protein name | STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2) STE20 related adaptor beta |
Synonyms | ILPIP ALS2CR2 PRO1038 |
Description | FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity). . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . |
Accessions | ENST00000194530.8 [Q9C0K7-1] C9JSU7 ENST00000458269.6 ENST00000415688.1 ENST00000447698.5 F8WCQ7 H7C3S5 Q9C0K7 ENST00000392249.6 [Q9C0K7-2] |