Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 6 studies | 26% ± 9% | |
| astrocyte | 4 studies | 34% ± 15% | |
| microglial cell | 4 studies | 22% ± 7% | |
| GABAergic neuron | 3 studies | 35% ± 17% | |
| oligodendrocyte precursor cell | 3 studies | 27% ± 9% | |
| interneuron | 3 studies | 37% ± 22% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 42% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 2911.59 | 2641 / 2642 | 89% | 2.13 | 630 / 705 |
| esophagus | 100% | 2308.78 | 1445 / 1445 | 80% | 1.63 | 147 / 183 |
| lung | 100% | 2410.61 | 578 / 578 | 63% | 1.41 | 722 / 1155 |
| ovary | 100% | 2731.87 | 180 / 180 | 56% | 1.04 | 239 / 430 |
| breast | 100% | 2373.93 | 459 / 459 | 55% | 1.10 | 614 / 1118 |
| skin | 100% | 2108.92 | 1809 / 1809 | 54% | 0.98 | 256 / 472 |
| pancreas | 99% | 1114.25 | 325 / 328 | 52% | 0.96 | 92 / 178 |
| thymus | 100% | 2577.39 | 653 / 653 | 49% | 0.84 | 296 / 605 |
| uterus | 100% | 2862.68 | 170 / 170 | 47% | 0.84 | 217 / 459 |
| kidney | 100% | 2291.04 | 89 / 89 | 45% | 0.89 | 406 / 901 |
| stomach | 100% | 1830.49 | 359 / 359 | 38% | 0.71 | 108 / 286 |
| bladder | 100% | 2511.67 | 21 / 21 | 36% | 0.79 | 183 / 504 |
| intestine | 100% | 2326.80 | 966 / 966 | 27% | 0.48 | 143 / 527 |
| adrenal gland | 100% | 2885.23 | 258 / 258 | 25% | 0.37 | 58 / 230 |
| prostate | 100% | 2725.28 | 245 / 245 | 17% | 0.25 | 85 / 502 |
| liver | 100% | 1317.34 | 226 / 226 | 11% | 0.18 | 45 / 406 |
| adipose | 100% | 2273.18 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3889.31 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2193.82 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 3062.33 | 921 / 929 | 0% | 0 | 0 / 0 |
| heart | 99% | 1553.62 | 853 / 861 | 0% | 0 | 0 / 0 |
| muscle | 98% | 904.26 | 786 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 76% | 1.75 | 22 / 29 |
| eye | 0% | 0 | 0 / 0 | 45% | 0.92 | 36 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 38% | 0.69 | 17 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0032147 | Biological process | activation of protein kinase activity |
| GO_0070314 | Biological process | G1 to G0 transition |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0006611 | Biological process | protein export from nucleus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0140535 | Cellular component | intracellular protein-containing complex |
| GO_1902554 | Cellular component | serine/threonine protein kinase complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0043539 | Molecular function | protein serine/threonine kinase activator activity |
| GO_0019900 | Molecular function | kinase binding |
| GO_0030295 | Molecular function | protein kinase activator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0004672 | Molecular function | protein kinase activity |
| Gene name | STRADA |
| Protein name | STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein) (Serologically defined breast cancer antigen NY-BR-96) STE20-related kinase adapter protein alpha (STE20-related adapter protein) STE20 related adaptor alpha |
| Synonyms | LYK5 STRAD |
| Description | FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . FUNCTION: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. . |
| Accessions | ENST00000638702.1 [Q7RTN6-5] A0A1W2PRQ6 A0A0G2JLH2 J3QQS3 ENST00000638708.1 ENST00000639135.1 ENST00000245865.10 ENST00000638276.1 ENST00000640870.1 J3KSA2 ENST00000447001.8 [Q7RTN6-4] ENST00000375840.9 [Q7RTN6-5] A0A1W2PQ20 A0A1W2PS04 A0A1W2PPG2 ENST00000639835.1 [Q7RTN6-3] Q86YC8 A0A1W2PPJ9 A0A1W2PQE8 ENST00000336174.12 [Q7RTN6-1] J3QRC1 A0A1W2PR44 ENST00000640999.1 [Q7RTN6-3] ENST00000578801.6 A0A1W2PPM8 ENST00000578008.6 ENST00000640741.1 J3QRH3 ENST00000584110.1 ENST00000581243.6 ENST00000579340.5 Q7RTN6 ENST00000640679.1 A0A1W2PRW9 ENST00000582026.2 J3QR78 A0A1W2PNV1 ENST00000639603.1 A0A1W2PRI8 A0A1W2PR65 ENST00000617949.4 ENST00000640397.1 ENST00000581505.6 J3QKR7 A0A1W2PR00 ENST00000638309.1 A0A1W2PQ00 ENST00000639521.1 A0A1W2PP17 ENST00000582030.5 ENST00000579549.6 J3QKU4 ENST00000640174.1 A0A1W2PNV7 ENST00000580039.6 ENST00000638888.1 A0A1W2PQF1 ENST00000392950.9 [Q7RTN6-2] ENST00000639164.1 ENST00000640086.1 ENST00000638718.1 J3KSK5 ENST00000582137.6 [Q7RTN6-6] A0A1W2PP78 ENST00000638193.1 ENST00000580338.5 ENST00000580288.2 A0A1W2PPI1 ENST00000638698.1 ENST00000640827.1 J3QS66 ENST00000640979.1 |
