STMN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007019Biological processmicrotubule depolymerization
GO_0010976Biological processpositive regulation of neuron projection development
GO_0031175Biological processneuron projection development
GO_0031115Biological processnegative regulation of microtubule polymerization
GO_0031110Biological processregulation of microtubule polymerization or depolymerization
GO_0007026Biological processnegative regulation of microtubule depolymerization
GO_0031117Biological processpositive regulation of microtubule depolymerization
GO_0010977Biological processnegative regulation of neuron projection development
GO_1990090Biological processcellular response to nerve growth factor stimulus
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0016020Cellular componentmembrane
GO_0005794Cellular componentGolgi apparatus
GO_0043025Cellular componentneuronal cell body
GO_0043005Cellular componentneuron projection
GO_0005829Cellular componentcytosol
GO_0030426Cellular componentgrowth cone
GO_0005737Cellular componentcytoplasm
GO_0005768Cellular componentendosome
GO_0030027Cellular componentlamellipodium
GO_0015631Molecular functiontubulin binding
GO_0048306Molecular functioncalcium-dependent protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSTMN2
Protein nameStathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10)
Stathmin
SynonymsSCGN10
SCG10
DescriptionFUNCTION: Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity). .

AccessionsENST00000518111.5 [Q93045-2]
Q93045
ENST00000220876.12 [Q93045-1]
ENST00000518491.1
E5RGX5