STAR report

I. Expression across cell types

Insufficient scRNA-seq data for expression of STAR at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of STAR at tissue level.

III. Associated gene sets

GO_0044255Biological processcellular lipid metabolic process
GO_0070859Biological processpositive regulation of bile acid biosynthetic process
GO_0008203Biological processcholesterol metabolic process
GO_0032367Biological processintracellular cholesterol transport
GO_0008211Biological processglucocorticoid metabolic process
GO_0006694Biological processsteroid biosynthetic process
GO_0050810Biological processregulation of steroid biosynthetic process
GO_0005758Cellular componentmitochondrial intermembrane space
GO_0005759Cellular componentmitochondrial matrix
GO_0015485Molecular functioncholesterol binding
GO_0005515Molecular functionprotein binding
GO_0120020Molecular functioncholesterol transfer activity

IV. Literature review

[source]
Gene nameSTAR
Protein nameSteroidogenic acute regulatory protein, mitochondrial (START domain-containing protein 1)
Mutant mitochondrial steroidogenic acute regulatory protein
Steroidogenic acute regulatory protein, mitochondrial (StAR) (START domain-containing protein 1)
Truncated steroidogenic acute regulatory protein
Steroidogenic acute regulatory protein
Steroidogenic acute regulatory protein, mitochondrial (StAR) (START domain-containing protein 1) (StARD1)
Steroid acute regulatory protein
SynonymsSTARD1
hCG_23102
DescriptionFUNCTION: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. .

FUNCTION: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. .

AccessionsQ3LR71
Q6IBK0
A0A0S2Z4E8
ENST00000522050.1
G8FGB3
Q3LR72
H0YB94
Q6QNJ9
P49675
ENST00000276449.9
ENST00000521236.1
E5RH12