Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| microglial cell | 9 studies | 27% ± 10% | |
| glutamatergic neuron | 6 studies | 49% ± 21% | |
| endothelial cell | 4 studies | 23% ± 3% | |
| GABAergic neuron | 4 studies | 34% ± 14% | |
| interneuron | 4 studies | 31% ± 20% | |
| neuron | 3 studies | 19% ± 3% | |
| smooth muscle cell | 3 studies | 30% ± 7% | |
| oligodendrocyte precursor cell | 3 studies | 28% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 32% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 1014.47 | 962 / 966 | 98% | 11.93 | 514 / 527 |
| adrenal gland | 100% | 2333.85 | 258 / 258 | 95% | 9.43 | 219 / 230 |
| stomach | 98% | 455.76 | 353 / 359 | 95% | 10.06 | 273 / 286 |
| brain | 96% | 676.45 | 2547 / 2642 | 91% | 5.01 | 642 / 705 |
| skin | 98% | 746.96 | 1773 / 1809 | 84% | 7.59 | 396 / 472 |
| lung | 98% | 650.45 | 569 / 578 | 83% | 4.16 | 958 / 1155 |
| esophagus | 97% | 464.54 | 1402 / 1445 | 78% | 4.94 | 142 / 183 |
| pancreas | 78% | 201.62 | 256 / 328 | 96% | 5.99 | 171 / 178 |
| uterus | 94% | 442.59 | 159 / 170 | 76% | 3.59 | 349 / 459 |
| bladder | 90% | 599.76 | 19 / 21 | 75% | 6.11 | 379 / 504 |
| breast | 97% | 477.36 | 445 / 459 | 63% | 2.36 | 706 / 1118 |
| kidney | 74% | 269.63 | 66 / 89 | 71% | 5.63 | 642 / 901 |
| prostate | 90% | 335.37 | 221 / 245 | 38% | 1.04 | 189 / 502 |
| ovary | 100% | 1373.86 | 180 / 180 | 26% | 0.74 | 111 / 430 |
| thymus | 74% | 260.74 | 486 / 653 | 29% | 1.18 | 178 / 605 |
| liver | 63% | 166.63 | 142 / 226 | 41% | 1.71 | 166 / 406 |
| spleen | 100% | 1113.11 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 97% | 585.56 | 1167 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 16.59 | 27 / 29 |
| heart | 86% | 454.50 | 738 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 4.38 | 37 / 45 |
| peripheral blood | 71% | 788.44 | 664 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 66% | 212.16 | 881 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 31% | 1.08 | 25 / 80 |
| muscle | 14% | 29.81 | 110 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071233 | Biological process | cellular response to L-leucine |
| GO_0070536 | Biological process | protein K63-linked deubiquitination |
| GO_1904263 | Biological process | positive regulation of TORC1 signaling |
| GO_0006508 | Biological process | proteolysis |
| GO_0005768 | Cellular component | endosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| GO_0140492 | Molecular function | metal-dependent deubiquitinase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0061578 | Molecular function | K63-linked deubiquitinase activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | STAMBPL1 |
| Protein name | AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1) |
| Synonyms | KIAA1373 AMSHLP |
| Description | FUNCTION: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains . Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex . Does not cleave 'Lys-48'-linked polyubiquitin chains . . |
| Accessions | ENST00000371926.8 [Q96FJ0-1] ENST00000371927.7 [Q96FJ0-2] Q96FJ0 ENST00000371924.5 [Q96FJ0-1] |
