I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 5 studies | 38% ± 7% | |
| Mueller cell | 5 studies | 63% ± 21% | |
| amacrine cell | 3 studies | 30% ± 14% | |
| myoepithelial cell | 3 studies | 34% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 5 studies | 38% ± 7% | |
| Mueller cell | 5 studies | 63% ± 21% | |
| amacrine cell | 3 studies | 30% ± 14% | |
| myoepithelial cell | 3 studies | 34% ± 5% |
Insufficient scRNA-seq data for expression of STAC2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 80% | 3058.27 | 2114 / 2642 | 83% | 23.00 | 585 / 705 |
| breast | 64% | 10933.88 | 295 / 459 | 59% | 48.13 | 663 / 1118 |
| kidney | 89% | 1888.06 | 79 / 89 | 28% | 32.07 | 253 / 901 |
| blood vessel | 86% | 7983.06 | 1154 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 38% | 729.97 | 93 / 245 | 48% | 3.30 | 243 / 502 |
| skin | 67% | 5157.51 | 1205 / 1809 | 19% | 2.39 | 90 / 472 |
| uterus | 56% | 998.64 | 96 / 170 | 22% | 3.60 | 101 / 459 |
| ovary | 10% | 246.41 | 18 / 180 | 57% | 10.98 | 244 / 430 |
| eye | 0% | 0 | 0 / 0 | 30% | 7.64 | 24 / 80 |
| adrenal gland | 2% | 12.38 | 4 / 258 | 27% | 3.39 | 61 / 230 |
| pancreas | 0% | 0 | 0 / 328 | 15% | 1.22 | 26 / 178 |
| lung | 2% | 22.93 | 12 / 578 | 8% | 2.32 | 97 / 1155 |
| esophagus | 2% | 19.15 | 26 / 1445 | 8% | 0.34 | 14 / 183 |
| adipose | 8% | 217.92 | 91 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.24 | 3 / 45 |
| heart | 6% | 76.61 | 53 / 861 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 4% | 0.77 | 22 / 504 |
| intestine | 1% | 12.57 | 8 / 966 | 3% | 0.42 | 15 / 527 |
| thymus | 0% | 3.23 | 2 / 653 | 3% | 0.32 | 17 / 605 |
| liver | 0% | 0 | 0 / 226 | 3% | 0.27 | 12 / 406 |
| stomach | 1% | 6.36 | 3 / 359 | 1% | 0.79 | 3 / 286 |
| muscle | 0% | 3.38 | 3 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1903078 | Biological process | positive regulation of protein localization to plasma membrane |
| GO_1901387 | Biological process | positive regulation of voltage-gated calcium channel activity |
| GO_0003009 | Biological process | skeletal muscle contraction |
| GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
| GO_0042383 | Cellular component | sarcolemma |
| GO_0005829 | Cellular component | cytosol |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | STAC2 |
| Protein name | SH3 and cysteine rich domain 2 SH3 and cysteine-rich domain-containing protein 2 (24b2/STAC2) (Src homology 3 and cysteine-rich domain-containing protein 2) SH3 and cysteine rich domain 2, isoform CRA_b (SH3 and cysteine-rich domain-containing protein 2) |
| Synonyms | hCG_31410 |
| Description | FUNCTION: Plays a redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C. . |
| Accessions | Q6ZMT1 ENST00000584501.1 D0IN09 ENST00000333461.6 [Q6ZMT1-1] J3QKZ0 |
