ST6GALNAC4 | OmnibusX

Name	Number of supported studies	Average coverage
plasmacytoid dendritic cell	17 studies	38% ± 12%	Explore
plasma cell	9 studies	36% ± 12%	Explore
plasmablast	6 studies	36% ± 17%	Explore
precursor B cell	3 studies	25% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ST6GALNAC4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1221.63	1445 / 1445	100%	32.56	183 / 183
ovary	100%	1993.23	180 / 180	100%	47.51	430 / 430
lung	100%	2469.27	578 / 578	99%	41.78	1146 / 1155
thymus	100%	1023.74	652 / 653	99%	27.63	600 / 605
pancreas	100%	3038.51	328 / 328	99%	29.78	176 / 178
intestine	100%	1484.79	966 / 966	99%	40.26	521 / 527
stomach	100%	974.19	358 / 359	99%	40.71	283 / 286
uterus	100%	1397.84	170 / 170	98%	36.34	452 / 459
brain	98%	800.24	2599 / 2642	100%	27.92	705 / 705
kidney	100%	1433.52	89 / 89	96%	20.38	861 / 901
breast	100%	1378.17	459 / 459	95%	31.47	1067 / 1118
bladder	100%	1444.76	21 / 21	94%	28.35	472 / 504
adrenal gland	100%	1251.84	258 / 258	87%	23.75	200 / 230
skin	97%	1024.05	1762 / 1809	85%	19.74	399 / 472
prostate	100%	1171.30	245 / 245	67%	7.45	336 / 502
liver	50%	380.15	113 / 226	56%	8.89	228 / 406
lymph node	0%	0	0 / 0	100%	81.02	29 / 29
spleen	100%	3186.44	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	9.19	1 / 1
adipose	100%	1519.26	1203 / 1204	0%	0	0 / 0
peripheral blood	100%	2386.63	927 / 929	0%	0	0 / 0
blood vessel	100%	1580.71	1332 / 1335	0%	0	0 / 0
heart	99%	1667.99	856 / 861	0%	0	0 / 0
muscle	99%	1081.60	798 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	29.05	44 / 45
eye	0%	0	0 / 0	70%	9.35	56 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0016266	Biological process	O-glycan processing
GO_0001574	Biological process	ganglioside biosynthetic process
GO_0019082	Biological process	viral protein processing
GO_0009311	Biological process	oligosaccharide metabolic process
GO_0006664	Biological process	glycolipid metabolic process
GO_0000139	Cellular component	Golgi membrane
GO_0047290	Molecular function	alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity
GO_0001665	Molecular function	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
GO_0008373	Molecular function	sialyltransferase activity

Gene name	ST6GALNAC4
Protein name	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (EC 2.4.3.7) (NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase) (ST6GalNAc IV) (ST6GalNAcIV) (Sialyltransferase 3C) (SIAT3-C) (Sialyltransferase 7D) (SIAT7-D) ST6 (Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4, isoform CRA_b (cDNA FLJ77235, highly similar to Homo sapiens ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 (ST6GALNAC4), transcript variant 3, mRNA) ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
Synonyms	SIAT3C SIAT7D hCG_2022909
Description	FUNCTION: Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of glycoproteins and glycolipids forming an alpha-2,6-linkage. Produces branched type disialyl structures by transfer of a sialyl group onto a GalNAc residue inside the backbone core chains. Prefers O-glycans to glycoproteins or glycolipids. .
Accessions	A8K7N4 Q9H4F1 ENST00000361444.3 A6NJX0 ENST00000335791.10

ST6GALNAC4 report