Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 12 studies | 34% ± 13% | |
type I pneumocyte | 10 studies | 24% ± 6% | |
oligodendrocyte precursor cell | 10 studies | 35% ± 13% | |
astrocyte | 9 studies | 36% ± 8% | |
type II pneumocyte | 8 studies | 32% ± 13% | |
GABAergic neuron | 6 studies | 40% ± 20% | |
glutamatergic neuron | 6 studies | 41% ± 24% | |
macrophage | 6 studies | 29% ± 7% | |
non-classical monocyte | 5 studies | 35% ± 20% | |
endothelial cell | 5 studies | 27% ± 5% | |
microglial cell | 5 studies | 22% ± 6% | |
retinal cone cell | 5 studies | 34% ± 18% | |
neuron | 4 studies | 27% ± 14% | |
retina horizontal cell | 4 studies | 37% ± 13% | |
retinal pigment epithelial cell | 4 studies | 48% ± 14% | |
mesothelial cell | 4 studies | 36% ± 18% | |
Mueller cell | 4 studies | 28% ± 4% | |
dendritic cell | 4 studies | 26% ± 5% | |
club cell | 4 studies | 29% ± 6% | |
interneuron | 4 studies | 42% ± 21% | |
granule cell | 3 studies | 17% ± 2% | |
B cell | 3 studies | 19% ± 2% | |
myeloid cell | 3 studies | 26% ± 13% | |
epithelial cell | 3 studies | 28% ± 6% | |
rod bipolar cell | 3 studies | 22% ± 2% | |
monocyte | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 3788.97 | 2640 / 2642 | 100% | 17.74 | 703 / 705 |
thymus | 100% | 7284.81 | 652 / 653 | 98% | 46.79 | 592 / 605 |
skin | 90% | 1180.49 | 1637 / 1809 | 99% | 27.23 | 465 / 472 |
adrenal gland | 100% | 9291.91 | 258 / 258 | 84% | 16.49 | 194 / 230 |
lung | 99% | 3203.92 | 574 / 578 | 62% | 10.06 | 718 / 1155 |
breast | 100% | 1853.66 | 457 / 459 | 52% | 2.83 | 582 / 1118 |
bladder | 100% | 4163.62 | 21 / 21 | 51% | 7.14 | 258 / 504 |
uterus | 98% | 2157.19 | 167 / 170 | 29% | 2.25 | 135 / 459 |
liver | 91% | 998.81 | 206 / 226 | 27% | 1.50 | 111 / 406 |
ovary | 99% | 2078.07 | 179 / 180 | 16% | 0.71 | 68 / 430 |
prostate | 97% | 1502.67 | 238 / 245 | 16% | 0.77 | 81 / 502 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.86 | 29 / 29 |
spleen | 100% | 4310.35 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 18.56 | 1 / 1 |
adipose | 99% | 2877.66 | 1196 / 1204 | 0% | 0 | 0 / 0 |
intestine | 92% | 1185.78 | 884 / 966 | 8% | 0.38 | 41 / 527 |
muscle | 97% | 1435.82 | 779 / 803 | 0% | 0 | 0 / 0 |
pancreas | 39% | 285.17 | 128 / 328 | 56% | 3.14 | 100 / 178 |
eye | 0% | 0 | 0 / 0 | 94% | 10.37 | 75 / 80 |
esophagus | 73% | 892.73 | 1062 / 1445 | 14% | 0.72 | 26 / 183 |
stomach | 71% | 867.33 | 255 / 359 | 11% | 0.55 | 31 / 286 |
kidney | 28% | 248.58 | 25 / 89 | 47% | 2.40 | 426 / 901 |
blood vessel | 62% | 592.46 | 827 / 1335 | 0% | 0 | 0 / 0 |
heart | 48% | 383.02 | 411 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 42% | 433.67 | 392 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 40% | 1.85 | 18 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001574 | Biological process | ganglioside biosynthetic process |
GO_0006688 | Biological process | glycosphingolipid biosynthetic process |
GO_0006486 | Biological process | protein glycosylation |
GO_0000139 | Cellular component | Golgi membrane |
GO_0016020 | Cellular component | membrane |
GO_0008373 | Molecular function | sialyltransferase activity |
GO_0047291 | Molecular function | lactosylceramide alpha-2,3-sialyltransferase activity |
GO_0003836 | Molecular function | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity |
Gene name | ST3GAL5 |
Protein name | Lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.3.9) (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase) (GM3 synthase) (Ganglioside GM3 synthase) (ST3Gal V) (ST3GalV) (Sialyltransferase 9) Lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.3.9) (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase) (Ganglioside GM3 synthase) (ST3Gal V) (Sialyltransferase 9) ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
Synonyms | UNQ2510/PRO5998 hCG_34610 SIAT9 |
Description | FUNCTION: Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesis, development, and oncogenesis) . Mainly involved in the biosynthesis of ganglioside GM3 but can also use different glycolipids as substrate acceptors such as D-galactosylceramide (GalCer), asialo-GM2 (GA2) and asialo-GM1 (GA1), although less preferentially than beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer (LacCer) . . |
Accessions | A0A1W2PR24 ENST00000638321.1 ENST00000639945.1 ENST00000638542.1 A0A1W2PRP8 ENST00000639305.1 ENST00000433665.6 ENST00000638484.1 ENST00000640425.1 A0A1W2PR45 Q9UNP4 ENST00000640222.1 ENST00000640378.1 ENST00000638678.1 ENST00000640903.1 ENST00000640849.1 ENST00000639119.1 A0A1W2PRY1 A0A1W2PQM6 ENST00000638288.1 A0A0S2Z4S6 ENST00000640024.1 A0A1W2PQ40 ENST00000639184.1 A0A1W2PRD9 ENST00000638885.1 ENST00000640992.1 [Q9UNP4-2] ENST00000639311.1 ENST00000638572.2 [Q9UNP4-1] A0A1W2PPG4 A0A1W2PR43 A0A1W2PNZ0 ENST00000639421.1 ENST00000639432.1 [Q9UNP4-2] ENST00000640314.1 A0A1W2PPT1 ENST00000638178.1 A0A1W2PQH5 E7EPY0 ENST00000455892.1 A0A1W2PPQ6 A0A1W2PQB4 F8WEA8 ENST00000639820.1 ENST00000377332.8 ENST00000639981.1 ENST00000639541.1 A0A0S2Z4Q7 ENST00000306262.10 A0A1W2PRC6 ENST00000638258.1 A0A1W2PR69 ENST00000639608.1 A0A1W2PNV2 ENST00000638523.1 A0A1W2PP52 A0A1W2PQT6 ENST00000640763.1 A0A1W2PQR0 ENST00000639690.1 A0A1W2PQ22 C9JYS9 A0A1W2PQ01 ENST00000639519.1 A0A1W2PP82 ENST00000640835.1 ENST00000640572.1 A0A1W2PNR4 ENST00000640418.1 ENST00000640315.1 ENST00000638956.1 A0A1W2PP90 ENST00000639202.1 A0A1W2PRT0 A0A1W2PPB0 ENST00000640322.1 [Q9UNP4-2] ENST00000638659.1 ENST00000638986.1 [Q9UNP4-2] A0A1W2PQ08 ENST00000640594.1 ENST00000640295.1 ENST00000640982.1 [Q9UNP4-2] A0A1W2PPF6 ENST00000638855.1 ENST00000393805.6 [Q9UNP4-2] ENST00000393808.8 [Q9UNP4-3] ENST00000638227.1 ENST00000473122.6 A0A1W2PQQ6 A0A1X7SBT2 |