SSH3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SSH3 at tissue level.

III. Associated gene sets

GO_0030036Biological processactin cytoskeleton organization
GO_0030837Biological processnegative regulation of actin filament polymerization
GO_0005856Cellular componentcytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004725Molecular functionprotein tyrosine phosphatase activity
GO_0004721Molecular functionphosphoprotein phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding
GO_0017018Molecular functionmyosin phosphatase activity

IV. Literature review

[source]
Gene nameSSH3
Protein nameProtein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L)
Alternative protein SSH3
Slingshot protein phosphatase 3
protein-serine/threonine phosphatase (EC 3.1.3.16)
Slingshot homolog 3 (Drosophila), isoform CRA_e (Slingshot protein phosphatase 3)
SynonymsSSH3L
hCG_21061
DescriptionFUNCTION: Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity). .

AccessionsENST00000532600.1
ENST00000308127.9 [Q8TE77-1]
E9PMS1
L8EA09
A0A087WWG1
Q8TE77
C9JUG3
ENST00000527821.2
ENST00000308298.11
ENST00000532181.5
E9PIT5
ENST00000532881.5 [Q8TE77-2]
ENST00000376757.9 [Q8TE77-3]