SRXN1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SRXN1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SRXN1 at tissue level.

III. Associated gene sets

GO_0034599Biological processcellular response to oxidative stress
GO_0098869Biological processcellular oxidant detoxification
GO_0006979Biological processresponse to oxidative stress
GO_0005737Cellular componentcytoplasm
GO_0005829Cellular componentcytosol
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0016667Molecular functionoxidoreductase activity, acting on a sulfur group of donors
GO_0032542Molecular functionsulfiredoxin activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameSRXN1
Protein nameHBV preS1-transactivated protein 5 (Sulfiredoxin 1 homolog (S. cerevisiae), isoform CRA_a) (cDNA FLJ25552 fis, clone JTH02127)
Sulfiredoxin-1 (EC 1.8.98.2)
SynonymsSRX
hCG_1641060
C20orf139
PS1TP5
SRX1
DescriptionFUNCTION: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4 . Does not act on PRDX5 or PRDX6 . May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase . .

AccessionsENST00000381962.4
Q9BYN0
Q8N7H8