I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| type I pneumocyte | 8 studies | 31% ± 13% | |
| B cell | 4 studies | 20% ± 4% | |
| epithelial cell | 4 studies | 29% ± 9% | |
| ciliated cell | 3 studies | 25% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| type I pneumocyte | 8 studies | 31% ± 13% | |
| B cell | 4 studies | 20% ± 4% | |
| epithelial cell | 4 studies | 29% ± 9% | |
| ciliated cell | 3 studies | 25% ± 2% |
Insufficient scRNA-seq data for expression of SPRING1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 5342.11 | 578 / 578 | 100% | 30.30 | 1154 / 1155 |
| thymus | 100% | 8674.02 | 653 / 653 | 100% | 108.72 | 604 / 605 |
| brain | 100% | 2779.30 | 2641 / 2642 | 100% | 33.15 | 704 / 705 |
| esophagus | 100% | 1235.25 | 1441 / 1445 | 100% | 22.56 | 183 / 183 |
| stomach | 100% | 2258.73 | 358 / 359 | 100% | 25.05 | 286 / 286 |
| breast | 100% | 1290.90 | 459 / 459 | 99% | 26.43 | 1112 / 1118 |
| skin | 100% | 1818.10 | 1809 / 1809 | 99% | 32.07 | 469 / 472 |
| intestine | 100% | 1596.02 | 964 / 966 | 99% | 24.57 | 524 / 527 |
| kidney | 100% | 2803.64 | 89 / 89 | 98% | 27.84 | 884 / 901 |
| bladder | 100% | 986.19 | 21 / 21 | 97% | 19.14 | 490 / 504 |
| uterus | 99% | 1060.68 | 169 / 170 | 98% | 17.44 | 448 / 459 |
| pancreas | 98% | 1129.84 | 320 / 328 | 98% | 18.06 | 174 / 178 |
| prostate | 100% | 1090.00 | 244 / 245 | 94% | 12.19 | 473 / 502 |
| ovary | 97% | 892.99 | 174 / 180 | 96% | 14.63 | 411 / 430 |
| adrenal gland | 100% | 1847.95 | 258 / 258 | 86% | 11.52 | 197 / 230 |
| liver | 75% | 841.07 | 170 / 226 | 58% | 9.16 | 234 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 26.06 | 29 / 29 |
| spleen | 100% | 1666.66 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 19.33 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.14 | 1 / 1 |
| adipose | 100% | 1222.01 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 20.98 | 79 / 80 |
| blood vessel | 94% | 864.09 | 1250 / 1335 | 0% | 0 | 0 / 0 |
| heart | 91% | 739.34 | 786 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 73% | 1040.26 | 682 / 929 | 0% | 0 | 0 / 0 |
| muscle | 25% | 135.15 | 197 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_2000640 | Biological process | positive regulation of SREBP signaling pathway |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SPRING1 |
| Protein name | SREBP regulating gene protein (SREBF pathway regulator in Golgi 1) SREBP regulating gene protein SREBF pathway regulator in golgi 1 |
| Synonyms | SPRING C12orf49 |
| Description | FUNCTION: Positively regulates hepatic SREBP signaling pathway by modulating the proper localization of SCAP (SREBP cleavage-activating protein) to the endoplasmic reticulum, thereby controlling the level of functional SCAP. . |
| Accessions | ENST00000261318.5 ENST00000548356.1 H0YHS8 ENST00000547606.1 Q9H741 ENST00000547630.1 F8VPB4 F8VVN2 |
