SPDYE2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
glutamatergic neuron	4 studies	26% ± 9%	Explore
cardiac muscle cell	4 studies	27% ± 9%	Explore
adipocyte	4 studies	26% ± 9%	Explore
GABAergic neuron	3 studies	19% ± 3%	Explore
astrocyte	3 studies	16% ± 1%	Explore
club cell	3 studies	18% ± 3%	Explore

II. Expression across tissues

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	90%	6.48	1306 / 1445	85%	2.79	155 / 183
ovary	92%	8.49	166 / 180	51%	1.27	219 / 430
stomach	91%	6.49	328 / 359	36%	0.79	104 / 286
lung	93%	9.38	540 / 578	19%	0.43	223 / 1155
intestine	93%	8.30	894 / 966	14%	0.39	76 / 527
spleen	98%	11.78	237 / 241	0%	0	0 / 0
breast	89%	6.51	408 / 459	8%	0.20	93 / 1118
thymus	96%	12.26	629 / 653	0%	0.00	2 / 605
prostate	96%	9.44	235 / 245	1%	0.04	3 / 502
kidney	89%	7.04	79 / 89	6%	0.14	58 / 901
muscle	94%	8.07	757 / 803	0%	0	0 / 0
uterus	91%	8.48	155 / 170	1%	0.04	5 / 459
pancreas	90%	7.33	294 / 328	1%	0.03	2 / 178
adrenal gland	90%	5.46	232 / 258	0%	0.01	1 / 230
bladder	86%	6.95	18 / 21	4%	0.09	21 / 504
skin	87%	5.98	1567 / 1809	3%	0.03	12 / 472
peripheral blood	86%	8.31	797 / 929	0%	0	0 / 0
adipose	85%	5.74	1022 / 1204	0%	0	0 / 0
heart	85%	5.73	729 / 861	0%	0	0 / 0
brain	70%	3.77	1843 / 2642	8%	0.17	57 / 705
blood vessel	76%	4.31	1014 / 1335	0%	0	0 / 0
liver	73%	3.51	166 / 226	1%	0.03	6 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1