Insufficient scRNA-seq data for expression of SPDYC at single-cell level.
Insufficient scRNA-seq data for expression of SPDYC at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 80.23 | 226 / 226 | 78% | 6.60 | 318 / 406 |
| ureter | 0% | 0 | 0 / 0 | 100% | 91.88 | 1 / 1 |
| intestine | 42% | 1.66 | 409 / 966 | 50% | 2.67 | 266 / 527 |
| lung | 59% | 3.84 | 343 / 578 | 21% | 3.28 | 237 / 1155 |
| peripheral blood | 79% | 19.22 | 731 / 929 | 0% | 0 | 0 / 0 |
| stomach | 19% | 0.52 | 70 / 359 | 51% | 3.12 | 147 / 286 |
| spleen | 67% | 5.14 | 162 / 241 | 0% | 0 | 0 / 0 |
| breast | 35% | 2.13 | 162 / 459 | 31% | 20.63 | 351 / 1118 |
| esophagus | 19% | 0.54 | 271 / 1445 | 40% | 3.77 | 73 / 183 |
| pancreas | 44% | 1.37 | 143 / 328 | 14% | 1.15 | 25 / 178 |
| ovary | 34% | 1.50 | 61 / 180 | 23% | 1.35 | 97 / 430 |
| uterus | 29% | 0.94 | 50 / 170 | 27% | 2.86 | 124 / 459 |
| kidney | 52% | 2.35 | 46 / 89 | 2% | 0.15 | 17 / 901 |
| bladder | 19% | 0.48 | 4 / 21 | 33% | 2.44 | 165 / 504 |
| brain | 49% | 1.80 | 1296 / 2642 | 1% | 0.01 | 5 / 705 |
| thymus | 33% | 1.10 | 217 / 653 | 0% | 0.01 | 2 / 605 |
| prostate | 33% | 1.18 | 81 / 245 | 0% | 0.00 | 1 / 502 |
| muscle | 31% | 1.01 | 252 / 803 | 0% | 0 | 0 / 0 |
| adipose | 27% | 0.95 | 330 / 1204 | 0% | 0 | 0 / 0 |
| skin | 20% | 0.57 | 361 / 1809 | 3% | 0.27 | 14 / 472 |
| heart | 21% | 0.58 | 181 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 19% | 0.66 | 48 / 258 | 0% | 0 | 0 / 230 |
| blood vessel | 18% | 0.49 | 238 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 18% | 0.84 | 8 / 45 |
| eye | 0% | 0 | 0 / 0 | 9% | 0.92 | 7 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.08 | 1 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SPDYC |
| Protein name | Speedy protein C (Rapid inducer of G2/M progression in oocytes C) (RINGO C) (hSpy/Ringo C) |
| Synonyms | |
| Description | FUNCTION: Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase. . |
| Accessions | ENST00000377185.3 Q5MJ68 |