SPATA7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045494Biological processphotoreceptor cell maintenance
GO_0007601Biological processvisual perception
GO_1903621Biological processprotein localization to photoreceptor connecting cilium
GO_1903546Biological processprotein localization to photoreceptor outer segment
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0005930Cellular componentaxoneme
GO_0036064Cellular componentciliary basal body
GO_0032391Cellular componentphotoreceptor connecting cilium
GO_0005829Cellular componentcytosol
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0120200Cellular componentrod photoreceptor outer segment
GO_0120206Cellular componentphotoreceptor distal connecting cilium
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSPATA7
Protein nameSpermatogenesis associated 7
Spermatogenesis-associated protein 7 (HSD-3.1) (Spermatogenesis-associated protein HSD3)
Epididymis secretory protein Li 296 (Spermatogenesis associated 7, isoform CRA_f)
SPATA7 protein
SynonymsHSD3
HEL-S-296
hCG_21084
DescriptionFUNCTION: Involved in the maintenance of both rod and cone photoreceptor cells (By similarity). It is required for recruitment and proper localization of RPGRIP1 to the photoreceptor connecting cilium (CC), as well as photoreceptor-specific localization of proximal CC proteins at the distal CC (By similarity). Maintenance of protein localization at the photoreceptor-specific distal CC is essential for normal microtubule stability and to prevent photoreceptor degeneration (By similarity). .

AccessionsG3V2V4
ENST00000556553.5 [Q9P0W8-2]
G3V5V8
ENST00000553885.5
ENST00000557724.5
G3V4A9
Q6FI63
G3V5H6
H0YJ93
ENST00000045347.11 [Q9P0W8-3]
ENST00000554802.1
G3V491
G3V287
ENST00000556406.5
G3V5N2
Q9P0W8
ENST00000393545.9 [Q9P0W8-1]
ENST00000555515.5
V9HVY9
G3V3D2
ENST00000553908.5
ENST00000356583.9 [Q9P0W8-2]
ENST00000556870.5
G3V2E1
ENST00000555534.5
H0YJ48
ENST00000555401.5
ENST00000554168.5
ENST00000557248.5
ENST00000555356.5
ENST00000555715.5