SOSTDC1 | OmnibusX

Name	Number of supported studies	Average coverage
myofibroblast cell	4 studies	30% ± 10%	Explore
capillary endothelial cell	3 studies	26% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SOSTDC1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	92%	362.66	884 / 966	55%	6.97	288 / 527
lung	97%	1257.78	559 / 578	48%	19.71	556 / 1155
stomach	89%	827.96	321 / 359	48%	7.90	136 / 286
kidney	89%	348.30	79 / 89	42%	83.77	376 / 901
esophagus	52%	92.57	752 / 1445	59%	23.11	108 / 183
skin	72%	734.19	1296 / 1809	33%	24.73	158 / 472
breast	57%	449.73	260 / 459	38%	10.05	423 / 1118
ovary	11%	11.07	20 / 180	53%	14.19	229 / 430
thymus	54%	117.87	355 / 653	10%	0.85	59 / 605
bladder	33%	108.76	7 / 21	25%	5.13	126 / 504
prostate	34%	46.71	83 / 245	17%	1.02	84 / 502
brain	31%	88.38	828 / 2642	13%	1.06	94 / 705
tonsil	0%	0	0 / 0	36%	9.44	16 / 45
heart	34%	100.13	290 / 861	0%	0	0 / 0
pancreas	1%	1.00	3 / 328	31%	4.33	56 / 178
uterus	3%	10.81	5 / 170	28%	8.66	129 / 459
eye	0%	0	0 / 0	25%	3.43	20 / 80
adrenal gland	3%	3.86	9 / 258	6%	1.01	14 / 230
liver	0%	0	0 / 226	7%	0.80	29 / 406
adipose	6%	11.15	72 / 1204	0%	0	0 / 0
blood vessel	4%	5.85	56 / 1335	0%	0	0 / 0
muscle	1%	1.93	12 / 803	0%	0	0 / 0
spleen	1%	1.59	2 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0042475	Biological process	odontogenesis of dentin-containing tooth
GO_0030509	Biological process	BMP signaling pathway
GO_0030178	Biological process	negative regulation of Wnt signaling pathway
GO_0031069	Biological process	hair follicle morphogenesis
GO_0045662	Biological process	negative regulation of myoblast differentiation
GO_0072148	Biological process	epithelial cell fate commitment
GO_0060648	Biological process	mammary gland bud morphogenesis
GO_2000016	Biological process	negative regulation of determination of dorsal identity
GO_0030514	Biological process	negative regulation of BMP signaling pathway
GO_0090090	Biological process	negative regulation of canonical Wnt signaling pathway
GO_0060070	Biological process	canonical Wnt signaling pathway
GO_0007389	Biological process	pattern specification process
GO_0010454	Biological process	negative regulation of cell fate commitment
GO_0005615	Cellular component	extracellular space
GO_0098821	Molecular function	BMP receptor activity
GO_0036122	Molecular function	BMP binding

Gene name	SOSTDC1
Protein name	Sclerostin domain-containing protein 1 Sclerostin domain-containing protein 1 (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1)
Synonyms	tcag7.902 CDA019 hCG_19295 USAG1
Description	FUNCTION: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. .
Accessions	Q6X4U4 ENST00000307068.5 [Q6X4U4-1] ENST00000396652.1 [Q6X4U4-2] A4D125

SOSTDC1 report