SLN | OmnibusX

Name	Number of supported studies	Average coverage
Mueller cell	3 studies	61% ± 15%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLN at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	39%	89.40	1036 / 2642	82%	40.56	578 / 705
muscle	100%	58908.89	803 / 803	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	2.83	1 / 1
heart	78%	9686.30	675 / 861	0%	0	0 / 0
lung	36%	141.95	208 / 578	28%	1.13	319 / 1155
intestine	21%	63.62	202 / 966	28%	0.89	148 / 527
esophagus	28%	139.90	408 / 1445	17%	0.69	32 / 183
ovary	3%	6.09	6 / 180	33%	1.66	142 / 430
prostate	18%	341.99	43 / 245	17%	13.13	86 / 502
pancreas	1%	0.97	3 / 328	31%	1.05	56 / 178
tonsil	0%	0	0 / 0	31%	18.59	14 / 45
breast	6%	39.72	29 / 459	24%	1.22	267 / 1118
kidney	3%	7.71	3 / 89	26%	3.59	231 / 901
adipose	29%	113.02	348 / 1204	0%	0	0 / 0
stomach	4%	9.14	14 / 359	25%	0.90	71 / 286
skin	20%	55.20	370 / 1809	7%	2.33	35 / 472
adrenal gland	12%	50.91	31 / 258	14%	0.96	32 / 230
blood vessel	25%	308.25	338 / 1335	0%	0	0 / 0
bladder	5%	5.43	1 / 21	16%	1.25	83 / 504
uterus	1%	0.42	1 / 170	18%	14.83	82 / 459
thymus	9%	40.91	56 / 653	5%	1.21	33 / 605
eye	0%	0	0 / 0	11%	0.76	9 / 80
liver	2%	2.11	5 / 226	9%	0.39	36 / 406
lymph node	0%	0	0 / 0	10%	0.13	3 / 29
peripheral blood	8%	76.67	72 / 929	0%	0	0 / 0
spleen	1%	0.90	2 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_1901881	Biological process	positive regulation of protein depolymerization
GO_1901020	Biological process	negative regulation of calcium ion transmembrane transporter activity
GO_0070296	Biological process	sarcoplasmic reticulum calcium ion transport
GO_0051924	Biological process	regulation of calcium ion transport
GO_1901894	Biological process	regulation of ATPase-coupled calcium transmembrane transporter activity
GO_0090281	Biological process	negative regulation of calcium ion import
GO_1901077	Biological process	regulation of relaxation of muscle
GO_0043086	Biological process	negative regulation of catalytic activity
GO_0043242	Biological process	negative regulation of protein-containing complex disassembly
GO_1901877	Biological process	negative regulation of calcium ion binding
GO_1901895	Biological process	negative regulation of ATPase-coupled calcium transmembrane transporter activity
GO_0120162	Biological process	positive regulation of cold-induced thermogenesis
GO_0006816	Biological process	calcium ion transport
GO_0016020	Cellular component	membrane
GO_0016529	Cellular component	sarcoplasmic reticulum
GO_0033017	Cellular component	sarcoplasmic reticulum membrane
GO_0004857	Molecular function	enzyme inhibitor activity
GO_0051117	Molecular function	ATPase binding
GO_0005515	Molecular function	protein binding

Gene name	SLN
Protein name	Sarcolipin
Synonyms
Description	FUNCTION: Reversibly inhibits the activity of ATP2A1 and ATP2A2 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis (By similarity). .
Accessions	O00631 ENST00000305991.3 ENST00000525934.1 A0A158RFT9 ENST00000531293.1

SLN report