SLIT1 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	10 studies	44% ± 21%	Explore
GABAergic neuron	6 studies	33% ± 13%	Explore
oligodendrocyte precursor cell	5 studies	27% ± 7%	Explore
interneuron	4 studies	40% ± 21%	Explore

Name	Number of supported studies	Average coverage
brain	7 studies	36% ± 19%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	86%	4799.43	2269 / 2642	98%	88.13	689 / 705
thymus	1%	4.61	6 / 653	76%	31.41	457 / 605
prostate	2%	75.90	4 / 245	70%	7.23	353 / 502
uterus	2%	7.62	3 / 170	16%	1.68	74 / 459
eye	0%	0	0 / 0	18%	1.42	14 / 80
pancreas	2%	10.02	7 / 328	14%	1.11	25 / 178
intestine	13%	53.45	124 / 966	3%	0.28	17 / 527
lymph node	0%	0	0 / 0	10%	1.29	3 / 29
lung	5%	27.42	27 / 578	5%	0.39	62 / 1155
breast	2%	5.09	7 / 459	8%	2.17	95 / 1118
ovary	2%	9.02	4 / 180	7%	0.45	30 / 430
stomach	2%	6.75	6 / 359	5%	0.28	13 / 286
skin	0%	1.52	5 / 1809	6%	0.28	28 / 472
adrenal gland	0%	2.83	1 / 258	4%	0.99	10 / 230
spleen	5%	15.74	11 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	4%	0.23	2 / 45
peripheral blood	4%	17.43	37 / 929	0%	0	0 / 0
adipose	4%	15.32	44 / 1204	0%	0	0 / 0
bladder	0%	0	0 / 21	3%	0.28	17 / 504
esophagus	0%	1.68	6 / 1445	2%	0.11	4 / 183
liver	0%	0	0 / 226	2%	0.08	7 / 406
kidney	0%	0	0 / 89	1%	0.05	8 / 901
blood vessel	0%	0.97	4 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008045	Biological process	motor neuron axon guidance
GO_0021834	Biological process	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
GO_0031290	Biological process	retinal ganglion cell axon guidance
GO_0048846	Biological process	axon extension involved in axon guidance
GO_0051964	Biological process	negative regulation of synapse assembly
GO_0048843	Biological process	negative regulation of axon extension involved in axon guidance
GO_0021510	Biological process	spinal cord development
GO_0048853	Biological process	forebrain morphogenesis
GO_0007411	Biological process	axon guidance
GO_0033563	Biological process	dorsal/ventral axon guidance
GO_0050919	Biological process	negative chemotaxis
GO_0007097	Biological process	nuclear migration
GO_0005615	Cellular component	extracellular space
GO_0008201	Molecular function	heparin binding
GO_0043395	Molecular function	heparan sulfate proteoglycan binding
GO_0048495	Molecular function	Roundabout binding
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

Gene name	SLIT1
Protein name	Slit guidance ligand 1 Slit homolog 1 protein (Slit-1) (Multiple epidermal growth factor-like domains protein 4) (Multiple EGF-like domains protein 4) Slit homolog 1 (Drosophila)
Synonyms	SLIL1 MEGF4 KIAA0813
Description	FUNCTION: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. .
Accessions	ENST00000371041.3 ENST00000371070.8 ENST00000314867.9 A6H8V1 O75093 ENST00000266058.9 [O75093-1] Q5T0V0 Q5T0V2 Q5T0V4

SLIT1 report