SLC7A9 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	6 studies	33% ± 16%	Explore
epithelial cell of proximal tubule	3 studies	19% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC7A9 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	588.64	226 / 226	94%	16.26	380 / 406
kidney	100%	1200.90	89 / 89	80%	15.27	718 / 901
ovary	100%	88.13	180 / 180	33%	0.74	140 / 430
intestine	95%	1708.32	913 / 966	25%	1.60	130 / 527
uterus	99%	77.58	169 / 170	17%	0.62	76 / 459
esophagus	84%	37.30	1217 / 1445	30%	1.74	54 / 183
brain	95%	69.87	2509 / 2642	18%	0.31	130 / 705
thymus	100%	98.25	651 / 653	10%	0.15	62 / 605
bladder	90%	46.33	19 / 21	19%	0.59	96 / 504
prostate	98%	115.78	241 / 245	10%	0.14	48 / 502
breast	88%	36.66	403 / 459	16%	0.26	181 / 1118
lung	79%	27.12	458 / 578	22%	1.40	255 / 1155
stomach	64%	20.47	230 / 359	35%	2.85	101 / 286
spleen	94%	38.73	227 / 241	0%	0	0 / 0
pancreas	61%	15.34	199 / 328	31%	1.40	55 / 178
blood vessel	83%	27.92	1102 / 1335	0%	0	0 / 0
adipose	78%	25.33	940 / 1204	0%	0	0 / 0
adrenal gland	59%	14.93	151 / 258	5%	0.07	12 / 230
skin	63%	20.89	1133 / 1809	1%	0.01	3 / 472
heart	48%	12.09	409 / 861	0%	0	0 / 0
muscle	26%	5.25	211 / 803	0%	0	0 / 0
peripheral blood	19%	4.03	181 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	7%	0.09	3 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0015811	Biological process	L-cystine transport
GO_0015804	Biological process	neutral amino acid transport
GO_1990822	Biological process	basic amino acid transmembrane transport
GO_0003333	Biological process	amino acid transmembrane transport
GO_1902475	Biological process	L-alpha-amino acid transmembrane transport
GO_0065003	Biological process	protein-containing complex assembly
GO_0031526	Cellular component	brush border membrane
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0046982	Molecular function	protein heterodimerization activity
GO_0015175	Molecular function	neutral L-amino acid transmembrane transporter activity
GO_0042605	Molecular function	peptide antigen binding
GO_0015297	Molecular function	antiporter activity
GO_0180009	Molecular function	broad specificity neutral L-amino acid:basic L-amino acid antiporter activity
GO_0005515	Molecular function	protein binding
GO_0015184	Molecular function	L-cystine transmembrane transporter activity

Gene name	SLC7A9
Protein name	Solute carrier family 7 member 9 b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)
Synonyms	BAT1
Description	FUNCTION: Associates with SLC3A1 to form a functional transporter complex that mediates the electrogenic exchange between cationic amino acids and neutral amino acids, with a stoichiometry of 1:1 . Has system b(0,+)-like activity with high affinity for extracellular cationic amino acids and L-cystine and lower affinity for intracellular neutral amino acids . Substrate exchange is driven by high concentration of intracellular neutral amino acids and the intracellular reduction of L-cystine to L-cysteine . Required for reabsorption of L-cystine and dibasic amino acids across the brush border membrane in renal proximal tubules. .
Accessions	ENST00000023064.9 ENST00000587772.1 P82251 ENST00000592232.5 ENST00000590465.5 K7EKD0 ENST00000590341.5

SLC7A9 report