Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 31 studies | 33% ± 13% | |
classical monocyte | 24 studies | 40% ± 15% | |
non-classical monocyte | 24 studies | 53% ± 16% | |
monocyte | 19 studies | 32% ± 10% | |
myeloid cell | 9 studies | 30% ± 10% | |
alveolar macrophage | 8 studies | 42% ± 17% | |
epithelial cell of proximal tubule | 7 studies | 33% ± 9% | |
enterocyte | 6 studies | 29% ± 7% | |
microglial cell | 6 studies | 22% ± 6% | |
conventional dendritic cell | 5 studies | 31% ± 8% | |
dendritic cell | 5 studies | 27% ± 8% | |
mononuclear phagocyte | 3 studies | 30% ± 16% | |
leukocyte | 3 studies | 21% ± 5% | |
tissue-resident macrophage | 3 studies | 21% ± 6% | |
intermediate monocyte | 3 studies | 66% ± 7% | |
neutrophil | 3 studies | 24% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 4 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 3592.05 | 578 / 578 | 94% | 19.56 | 1086 / 1155 |
breast | 92% | 738.15 | 420 / 459 | 95% | 14.05 | 1057 / 1118 |
kidney | 93% | 8436.62 | 83 / 89 | 89% | 39.81 | 804 / 901 |
intestine | 84% | 2040.19 | 811 / 966 | 93% | 17.57 | 492 / 527 |
thymus | 85% | 577.03 | 554 / 653 | 84% | 8.20 | 508 / 605 |
stomach | 68% | 489.88 | 245 / 359 | 98% | 19.65 | 279 / 286 |
bladder | 90% | 610.52 | 19 / 21 | 67% | 10.59 | 336 / 504 |
uterus | 76% | 470.67 | 129 / 170 | 74% | 8.99 | 339 / 459 |
pancreas | 46% | 269.89 | 151 / 328 | 95% | 30.85 | 169 / 178 |
esophagus | 48% | 314.23 | 692 / 1445 | 80% | 15.20 | 147 / 183 |
skin | 39% | 208.94 | 701 / 1809 | 81% | 13.10 | 382 / 472 |
adrenal gland | 81% | 649.58 | 210 / 258 | 28% | 2.23 | 64 / 230 |
ovary | 24% | 145.41 | 44 / 180 | 83% | 11.38 | 355 / 430 |
lymph node | 0% | 0 | 0 / 0 | 100% | 47.00 | 29 / 29 |
spleen | 100% | 7803.18 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 7798.35 | 927 / 929 | 0% | 0 | 0 / 0 |
brain | 15% | 99.65 | 405 / 2642 | 83% | 13.18 | 586 / 705 |
adipose | 97% | 1309.41 | 1166 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 92% | 1067.30 | 1222 / 1335 | 0% | 0 | 0 / 0 |
prostate | 58% | 410.14 | 142 / 245 | 32% | 2.05 | 161 / 502 |
tonsil | 0% | 0 | 0 / 0 | 84% | 13.39 | 38 / 45 |
liver | 37% | 242.60 | 83 / 226 | 46% | 6.30 | 188 / 406 |
heart | 37% | 237.89 | 315 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 36% | 2.71 | 29 / 80 |
muscle | 1% | 5.66 | 10 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1903826 | Biological process | L-arginine transmembrane transport |
GO_0000821 | Biological process | regulation of arginine metabolic process |
GO_1990822 | Biological process | basic amino acid transmembrane transport |
GO_0003333 | Biological process | amino acid transmembrane transport |
GO_0015820 | Biological process | L-leucine transport |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0061459 | Molecular function | L-arginine transmembrane transporter activity |
GO_0015179 | Molecular function | L-amino acid transmembrane transporter activity |
GO_0005515 | Molecular function | protein binding |
GO_0015174 | Molecular function | basic amino acid transmembrane transporter activity |
Gene name | SLC7A7 |
Protein name | Y+L amino acid transporter 1 (Monocyte amino acid permease 2) (MOP-2) (Solute carrier family 7 member 7) (y(+)L-type amino acid transporter 1) (Y+LAT1) (y+LAT-1) Solute carrier family 7 member 7 isoform 3 Solute carrier family 7 member 7 isoform 4 Y+L amino acid transporter 1 Solute carrier family 7 member 7 Solute carrier family 7 member 7 isoform 1 |
Synonyms | |
Description | FUNCTION: Heterodimer with SLC3A2, that functions as an antiporter which operates as an efflux route by exporting cationic amino acids from inside the cells in exchange with neutral amino acids plus sodium ions and may participate in nitric oxide synthesis via the transport of L-arginine . Also mediates arginine transport in non-polarized cells, such as monocytes, and is essential for the correct function of these cells . The transport mechanism is electroneutral and operates with a stoichiometry of 1:1 (By similarity). In vitro, Na(+) and Li(+), but also H(+), are cotransported with the neutral amino acids (By similarity). . |
Accessions | ENST00000698939.1 G3V2K0 G3V4U1 ENST00000556287.5 ENST00000555959.1 G3V2H8 ENST00000556350.1 D6RFE5 ENST00000397528.8 G3V5W2 G3V2L0 G3V4Z6 G3V362 G3V5A1 ENST00000554758.1 ENST00000397529.6 ENST00000555911.1 ENST00000555911.2 ENST00000488800.5 A0A8V8TP95 ENST00000554517.5 G3V273 ENST00000285850.11 H0YJ95 A0A0S2Z4W9 ENST00000555702.5 ENST00000557629.5 ENST00000555251.1 A0A0S2Z502 A0A0S2Z4V9 ENST00000554741.5 ENST00000557129.5 Q9UM01 ENST00000397532.9 ENST00000674313.1 |