SLC6A20 | OmnibusX

Name	Number of supported studies	Average coverage
retinal pigment epithelial cell	4 studies	39% ± 6%	Explore
epithelial cell	3 studies	30% ± 6%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC6A20 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	542.11	328 / 328	85%	18.47	152 / 178
kidney	92%	511.75	82 / 89	46%	10.46	411 / 901
stomach	61%	93.95	220 / 359	74%	14.29	212 / 286
intestine	40%	482.50	389 / 966	79%	16.69	415 / 527
lung	70%	368.59	403 / 578	31%	4.14	358 / 1155
breast	86%	140.24	393 / 459	5%	0.25	57 / 1118
uterus	74%	175.92	125 / 170	15%	2.61	71 / 459
esophagus	37%	29.80	540 / 1445	43%	13.27	78 / 183
muscle	73%	99.90	583 / 803	0%	0	0 / 0
brain	62%	80.63	1629 / 2642	4%	0.24	28 / 705
bladder	24%	9.76	5 / 21	23%	3.15	115 / 504
skin	44%	33.55	803 / 1809	0%	0	0 / 472
thymus	7%	5.30	45 / 653	35%	4.66	211 / 605
ovary	7%	6.44	13 / 180	23%	1.72	98 / 430
adipose	22%	23.83	267 / 1204	0%	0	0 / 0
liver	17%	9.93	38 / 226	4%	0.79	16 / 406
prostate	14%	8.59	35 / 245	0%	0.01	1 / 502
adrenal gland	14%	25.38	35 / 258	0%	0.02	1 / 230
eye	0%	0	0 / 0	11%	0.44	9 / 80
spleen	8%	3.06	20 / 241	0%	0	0 / 0
blood vessel	4%	2.33	52 / 1335	0%	0	0 / 0
peripheral blood	2%	2.28	21 / 929	0%	0	0 / 0
heart	1%	0.55	11 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0015838	Biological process	amino-acid betaine transport
GO_1905647	Biological process	proline import across plasma membrane
GO_0150104	Biological process	transport across blood-brain barrier
GO_1903806	Biological process	L-isoleucine import across plasma membrane
GO_0089718	Biological process	amino acid import across plasma membrane
GO_1903804	Biological process	glycine import across plasma membrane
GO_0015816	Biological process	glycine transport
GO_0015824	Biological process	proline transport
GO_0006865	Biological process	amino acid transport
GO_1904271	Biological process	L-proline import across plasma membrane
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0015188	Molecular function	L-isoleucine transmembrane transporter activity
GO_0015171	Molecular function	amino acid transmembrane transporter activity
GO_0015193	Molecular function	L-proline transmembrane transporter activity
GO_0015370	Molecular function	solute:sodium symporter activity
GO_0005298	Molecular function	proline:sodium symporter activity
GO_0015175	Molecular function	neutral L-amino acid transmembrane transporter activity
GO_0015199	Molecular function	amino-acid betaine transmembrane transporter activity
GO_0005515	Molecular function	protein binding

Gene name	SLC6A20
Protein name	Transporter Sodium- and chloride-dependent transporter XTRP3 (Sodium/imino-acid transporter 1) (Solute carrier family 6 member 20) (Transporter rB21A homolog)
Synonyms	SIT1 XTRP3 XT3
Description	FUNCTION: Mediates the Na(+)- and Cl(-)-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids . Also transports glycine, regulates proline and glycine homeostasis in the brain playing a role in the modulation of NMDAR currents . .
Accessions	ENST00000358525.9 [Q9NP91-1] B7ZLW4 ENST00000353278.8 [Q9NP91-2] Q9NP91 ENST00000703343.1 A0A8V8TQV4

SLC6A20 report