SLC6A19 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC6A19 at tissue level.

III. Associated gene sets

GO_0007584Biological processresponse to nutrient
GO_0006865Biological processamino acid transport
GO_0015804Biological processneutral amino acid transport
GO_0035725Biological processsodium ion transmembrane transport
GO_0019058Biological processviral life cycle
GO_0003333Biological processamino acid transmembrane transport
GO_0031526Cellular componentbrush border membrane
GO_0016324Cellular componentapical plasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0005886Cellular componentplasma membrane
GO_0015175Molecular functionneutral L-amino acid transmembrane transporter activity
GO_0015293Molecular functionsymporter activity
GO_0015171Molecular functionamino acid transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC6A19
Protein nameTransporter
Alternative protein SLC6A19
Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1)
SynonymsB0AT1
DescriptionFUNCTION: Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells . This uptake is sodium-dependent and chloride-independent . Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity . .

AccessionsQ695T7
L8E8F7
ENST00000304460.11
E9PD72
ENST00000515652.5