Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 7 studies | 39% ± 26% | |
| interneuron | 5 studies | 37% ± 23% | |
| GABAergic neuron | 5 studies | 40% ± 20% | |
| oligodendrocyte | 5 studies | 28% ± 9% | |
| neuron | 3 studies | 24% ± 7% | |
| retinal ganglion cell | 3 studies | 41% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 37% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 60% | 1025.61 | 1086 / 1809 | 90% | 29.30 | 423 / 472 |
| brain | 97% | 1779.73 | 2557 / 2642 | 38% | 2.80 | 265 / 705 |
| eye | 0% | 0 | 0 / 0 | 99% | 26.53 | 79 / 80 |
| esophagus | 35% | 202.51 | 511 / 1445 | 42% | 4.89 | 77 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 3.27 | 26 / 45 |
| uterus | 15% | 42.72 | 26 / 170 | 24% | 2.14 | 108 / 459 |
| lung | 0% | 0 | 0 / 578 | 28% | 3.49 | 326 / 1155 |
| ovary | 3% | 8.47 | 6 / 180 | 22% | 1.28 | 94 / 430 |
| breast | 14% | 39.68 | 62 / 459 | 8% | 1.07 | 94 / 1118 |
| adrenal gland | 2% | 7.05 | 6 / 258 | 19% | 1.80 | 44 / 230 |
| bladder | 5% | 10.86 | 1 / 21 | 9% | 0.63 | 46 / 504 |
| adipose | 14% | 46.59 | 167 / 1204 | 0% | 0 | 0 / 0 |
| intestine | 8% | 20.33 | 80 / 966 | 2% | 0.12 | 9 / 527 |
| kidney | 1% | 2.03 | 1 / 89 | 5% | 0.80 | 46 / 901 |
| prostate | 1% | 3.41 | 3 / 245 | 5% | 0.21 | 23 / 502 |
| thymus | 4% | 8.78 | 26 / 653 | 1% | 0.05 | 4 / 605 |
| liver | 0% | 0 | 0 / 226 | 3% | 0.30 | 13 / 406 |
| stomach | 1% | 2.39 | 3 / 359 | 2% | 0.12 | 5 / 286 |
| pancreas | 0% | 0 | 0 / 328 | 2% | 0.18 | 3 / 178 |
| blood vessel | 1% | 1.63 | 10 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0015824 | Biological process | proline transport |
| GO_0006865 | Biological process | amino acid transport |
| GO_0015804 | Biological process | neutral amino acid transport |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0015820 | Biological process | L-leucine transport |
| GO_0003333 | Biological process | amino acid transmembrane transport |
| GO_0006836 | Biological process | neurotransmitter transport |
| GO_1905039 | Biological process | carboxylic acid transmembrane transport |
| GO_0016020 | Cellular component | membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0015171 | Molecular function | amino acid transmembrane transporter activity |
| GO_0005326 | Molecular function | neurotransmitter transmembrane transporter activity |
| GO_0005298 | Molecular function | proline:sodium symporter activity |
| GO_0015657 | Molecular function | branched-chain amino acid:sodium symporter activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005295 | Molecular function | neutral L-amino acid:sodium symporter activity |
| Gene name | SLC6A15 |
| Protein name | Transporter Solute carrier family 6 member 15 Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3) |
| Synonyms | NTT73 B0AT2 SBAT1 |
| Description | FUNCTION: Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Can also transport low-affinity substrates such as alanine, phenylalanine, glutamine and pipecolic acid. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. . |
| Accessions | A0A7P0T826 ENST00000681721.1 [Q9H2J7-1] ENST00000680187.1 A0A7P0TB74 ENST00000680963.1 [Q9H2J7-1] ENST00000679933.1 A0A7P0T8B7 ENST00000680207.1 ENST00000679679.1 ENST00000680469.1 ENST00000679453.1 ENST00000679363.1 A0A7P0Z4F0 A0A7P0T8I1 Q9H2J7 A0A7P0T9P8 ENST00000549540.1 A0A7P0TA72 A0A7P0TAT1 ENST00000680379.1 A0A7P0TB05 ENST00000681688.1 [Q9H2J7-2] ENST00000679430.1 ENST00000680260.1 Q8TBM6 ENST00000309283.12 ENST00000680892.1 A0A7P0Z4M4 ENST00000681106.1 [Q9H2J7-1] ENST00000551010.2 ENST00000681281.1 ENST00000679989.1 A0A7P0TBL2 ENST00000680780.1 ENST00000552192.5 [Q9H2J7-3] ENST00000679681.1 ENST00000681220.1 ENST00000680714.1 ENST00000266682.10 [Q9H2J7-1] F8WJN6 A0A7P0T9G8 F8VSG1 ENST00000450363.4 [Q9H2J7-2] A0A7P0T9Z9 A0A7P0TAZ8 |
