Insufficient scRNA-seq data for expression of SLC5A5 at single-cell level.
Insufficient scRNA-seq data for expression of SLC5A5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 99% | 1435.22 | 647 / 653 | 30% | 10.48 | 179 / 605 |
| stomach | 80% | 3042.04 | 288 / 359 | 24% | 4.85 | 68 / 286 |
| spleen | 95% | 37.41 | 228 / 241 | 0% | 0 | 0 / 0 |
| lung | 49% | 24.10 | 286 / 578 | 26% | 3.06 | 306 / 1155 |
| peripheral blood | 69% | 23.06 | 639 / 929 | 0% | 0 | 0 / 0 |
| brain | 45% | 78.72 | 1177 / 2642 | 3% | 0.11 | 22 / 705 |
| prostate | 33% | 19.14 | 82 / 245 | 10% | 0.22 | 51 / 502 |
| esophagus | 8% | 4.58 | 122 / 1445 | 28% | 3.63 | 52 / 183 |
| intestine | 23% | 15.09 | 218 / 966 | 11% | 2.61 | 58 / 527 |
| uterus | 7% | 27.43 | 12 / 170 | 26% | 2.94 | 119 / 459 |
| ovary | 3% | 0.57 | 5 / 180 | 29% | 1.64 | 125 / 430 |
| bladder | 10% | 2.00 | 2 / 21 | 12% | 1.40 | 61 / 504 |
| breast | 10% | 10.51 | 47 / 459 | 10% | 0.67 | 108 / 1118 |
| pancreas | 4% | 0.80 | 13 / 328 | 12% | 1.01 | 21 / 178 |
| skin | 13% | 3.18 | 242 / 1809 | 2% | 0.23 | 11 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 1.63 | 4 / 29 |
| kidney | 9% | 1.96 | 8 / 89 | 2% | 0.06 | 15 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.11 | 3 / 45 |
| adipose | 6% | 2.21 | 76 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 6% | 1.77 | 76 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 2% | 1.43 | 4 / 258 | 3% | 0.11 | 6 / 230 |
| liver | 1% | 0.18 | 3 / 226 | 3% | 0.15 | 11 / 406 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.03 | 1 / 80 |
| heart | 1% | 0.33 | 10 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.26 | 6 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071371 | Biological process | cellular response to gonadotropin stimulus |
| GO_0006590 | Biological process | thyroid hormone generation |
| GO_1904200 | Biological process | iodide transmembrane transport |
| GO_0150104 | Biological process | transport across blood-brain barrier |
| GO_1904401 | Biological process | cellular response to Thyroid stimulating hormone |
| GO_0006811 | Biological process | monoatomic ion transport |
| GO_0015705 | Biological process | iodide transport |
| GO_0071320 | Biological process | cellular response to cAMP |
| GO_1904322 | Biological process | cellular response to forskolin |
| GO_0006814 | Biological process | sodium ion transport |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_1903561 | Cellular component | extracellular vesicle |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0008507 | Molecular function | sodium:iodide symporter activity |
| GO_0015373 | Molecular function | monoatomic anion:sodium symporter activity |
| GO_0015111 | Molecular function | iodide transmembrane transporter activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SLC5A5 |
| Protein name | Solute carrier family 5 member 5 Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Natrium iodide transporter) (Sodium-iodide symporter) (Na(+)/I(-) symporter) (Solute carrier family 5 member 5) |
| Synonyms | NIS |
| Description | FUNCTION: Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland . Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate . . |
| Accessions | Q92911 A0A5P9KGQ3 A0A2U8QNU8 ENST00000222248.4 |