SLC51B | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	7 studies	39% ± 16%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC51B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	97%	441.29	86 / 89	88%	15.72	795 / 901
intestine	96%	1208.54	931 / 966	76%	13.12	401 / 527
prostate	99%	144.54	242 / 245	64%	2.57	322 / 502
brain	63%	40.26	1662 / 2642	90%	11.41	634 / 705
lung	99%	192.53	574 / 578	44%	4.89	503 / 1155
liver	50%	45.69	113 / 226	83%	25.93	335 / 406
bladder	95%	60.14	20 / 21	31%	4.12	154 / 504
uterus	98%	108.89	167 / 170	21%	2.05	96 / 459
adrenal gland	64%	39.96	166 / 258	54%	6.52	125 / 230
stomach	46%	17.27	166 / 359	68%	11.19	195 / 286
esophagus	78%	55.22	1120 / 1445	27%	3.06	50 / 183
blood vessel	100%	196.36	1330 / 1335	0%	0	0 / 0
ovary	74%	42.67	134 / 180	18%	1.32	78 / 430
breast	59%	24.98	269 / 459	15%	0.66	171 / 1118
adipose	69%	31.50	833 / 1204	0%	0	0 / 0
heart	47%	17.74	408 / 861	0%	0	0 / 0
pancreas	8%	2.35	27 / 328	32%	1.61	57 / 178
spleen	40%	12.49	97 / 241	0%	0	0 / 0
thymus	23%	7.66	147 / 653	3%	0.11	18 / 605
skin	16%	5.12	284 / 1809	6%	0.34	28 / 472
muscle	4%	1.27	36 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	2%	0.27	1 / 45
peripheral blood	0%	0.12	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0015721	Biological process	bile acid and bile salt transport
GO_0031647	Biological process	regulation of protein stability
GO_0090314	Biological process	positive regulation of protein targeting to membrane
GO_0032782	Biological process	bile acid secretion
GO_0060050	Biological process	positive regulation of protein glycosylation
GO_0055085	Biological process	transmembrane transport
GO_0070863	Biological process	positive regulation of protein exit from endoplasmic reticulum
GO_0016323	Cellular component	basolateral plasma membrane
GO_0032991	Cellular component	protein-containing complex
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005215	Molecular function	transporter activity
GO_0046982	Molecular function	protein heterodimerization activity
GO_0015125	Molecular function	bile acid transmembrane transporter activity
GO_0005515	Molecular function	protein binding

Gene name	SLC51B
Protein name	Organic solute transporter subunit beta (OST-beta) (Solute carrier family 51 subunit beta)
Synonyms	OSTB
Description	FUNCTION: Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood . Modulates SLC51A glycosylation, membrane trafficking and stability activities . The Ost-alpha/Ost-beta complex efficiently transports the major species of bile acids (taurocholate) . Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (By similarity). Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols . Able to transport eicosanoids such as prostaglandin E2 (By similarity). .
Accessions	ENST00000334287.3 Q86UW2

SLC51B report