SLC51A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC51A at tissue level.

III. Associated gene sets

GO_0015721Biological processbile acid and bile salt transport
GO_0032782Biological processbile acid secretion
GO_0055085Biological processtransmembrane transport
GO_0016323Cellular componentbasolateral plasma membrane
GO_0032991Cellular componentprotein-containing complex
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0046982Molecular functionprotein heterodimerization activity
GO_0005215Molecular functiontransporter activity
GO_0042803Molecular functionprotein homodimerization activity
GO_0015125Molecular functionbile acid transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC51A
Protein nameOrganic solute transporter subunit alpha (OST-alpha) (Solute carrier family 51 subunit alpha)
Solute carrier family 51 subunit alpha
SynonymsOSTA
DescriptionFUNCTION: Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood . Efficiently transports the major species of bile acids (taurocholate) . Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (By similarity). Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols . Able to transport eicosanoids such as prostaglandin E2 (By similarity). .

AccessionsQ86UW1
ENST00000296327.10
F8WBV2
C9J2I5
H7C351
ENST00000428985.1
ENST00000416660.1
ENST00000442203.1
H7C3V2
ENST00000415111.1