SLC43A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015821Biological processmethionine transport
GO_0015823Biological processphenylalanine transport
GO_0051956Biological processnegative regulation of amino acid transport
GO_0015820Biological processL-leucine transport
GO_0015818Biological processisoleucine transport
GO_0015804Biological processneutral amino acid transport
GO_1902475Biological processL-alpha-amino acid transmembrane transport
GO_0006865Biological processamino acid transport
GO_1905533Biological processnegative regulation of L-leucine import across plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0016323Cellular componentbasolateral plasma membrane
GO_0015188Molecular functionL-isoleucine transmembrane transporter activity
GO_0015171Molecular functionamino acid transmembrane transporter activity
GO_0015179Molecular functionL-amino acid transmembrane transporter activity
GO_0015191Molecular functionL-methionine transmembrane transporter activity
GO_0015175Molecular functionneutral L-amino acid transmembrane transporter activity
GO_0015192Molecular functionL-phenylalanine transmembrane transporter activity
GO_0005515Molecular functionprotein binding
GO_0015190Molecular functionL-leucine transmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC43A2
Protein nameSLC43A2 protein
Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2)
Large neutral amino acids transporter small subunit 4 (Solute carrier family 43 member 2)
SynonymsPP7664
LAT4
DescriptionFUNCTION: Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine . The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent . .

AccessionsENST00000382147.8 [Q8N370-4]
ENST00000412517.3 [Q8N370-4]
I3L3E3
I3L4J2
ENST00000571376.1
ENST00000301335.10 [Q8N370-1]
I3L4V3
ENST00000631603.1
ENST00000634102.1 [Q8N370-1]
ENST00000633255.1
ENST00000613070.4 [Q8N370-3]
ENST00000572801.5
ENST00000612931.4 [Q8N370-3]
ENST00000633994.1
ENST00000576721.5
Q8WUU1
ENST00000571650.5 [Q8N370-3]
Q8N370