Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 31 studies | 25% ± 8% | |
classical monocyte | 23 studies | 29% ± 10% | |
non-classical monocyte | 18 studies | 32% ± 13% | |
monocyte | 15 studies | 32% ± 12% | |
conventional dendritic cell | 7 studies | 23% ± 5% | |
renal alpha-intercalated cell | 7 studies | 38% ± 5% | |
myeloid cell | 7 studies | 30% ± 12% | |
microglial cell | 6 studies | 23% ± 7% | |
dendritic cell | 6 studies | 28% ± 13% | |
ionocyte | 5 studies | 41% ± 17% | |
neutrophil | 5 studies | 21% ± 7% | |
mononuclear phagocyte | 4 studies | 25% ± 7% | |
endothelial cell | 3 studies | 23% ± 4% | |
glutamatergic neuron | 3 studies | 34% ± 23% | |
placental villous trophoblast | 3 studies | 67% ± 6% | |
epithelial cell | 3 studies | 26% ± 7% | |
tissue-resident macrophage | 3 studies | 26% ± 7% | |
ciliated cell | 3 studies | 21% ± 6% | |
alveolar macrophage | 3 studies | 35% ± 10% | |
neuron | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
placenta | 4 studies | 26% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 2367.26 | 653 / 653 | 100% | 15.24 | 602 / 605 |
kidney | 100% | 7320.99 | 89 / 89 | 99% | 30.33 | 896 / 901 |
lung | 100% | 4065.24 | 578 / 578 | 99% | 15.69 | 1138 / 1155 |
brain | 98% | 2613.21 | 2597 / 2642 | 100% | 22.42 | 705 / 705 |
breast | 100% | 2069.87 | 458 / 459 | 98% | 15.73 | 1101 / 1118 |
intestine | 98% | 1648.45 | 945 / 966 | 99% | 13.85 | 521 / 527 |
prostate | 98% | 1371.86 | 239 / 245 | 99% | 10.02 | 495 / 502 |
stomach | 93% | 1356.53 | 335 / 359 | 99% | 15.03 | 284 / 286 |
bladder | 90% | 1843.29 | 19 / 21 | 96% | 14.36 | 485 / 504 |
adrenal gland | 98% | 1451.37 | 252 / 258 | 87% | 10.91 | 200 / 230 |
esophagus | 70% | 830.48 | 1011 / 1445 | 97% | 14.49 | 177 / 183 |
uterus | 73% | 874.21 | 124 / 170 | 91% | 9.58 | 416 / 459 |
pancreas | 56% | 500.32 | 183 / 328 | 98% | 14.26 | 174 / 178 |
ovary | 54% | 514.06 | 98 / 180 | 98% | 13.20 | 421 / 430 |
skin | 59% | 581.43 | 1060 / 1809 | 81% | 7.13 | 384 / 472 |
lymph node | 0% | 0 | 0 / 0 | 100% | 20.07 | 29 / 29 |
spleen | 100% | 4979.66 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.71 | 1 / 1 |
muscle | 100% | 7902.15 | 802 / 803 | 0% | 0 | 0 / 0 |
adipose | 100% | 2333.92 | 1202 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 9946.43 | 927 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 12.30 | 44 / 45 |
blood vessel | 88% | 1196.45 | 1170 / 1335 | 0% | 0 | 0 / 0 |
liver | 18% | 178.94 | 41 / 226 | 66% | 5.68 | 268 / 406 |
heart | 45% | 445.68 | 384 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 44% | 2.29 | 35 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0015821 | Biological process | methionine transport |
GO_0015823 | Biological process | phenylalanine transport |
GO_0051956 | Biological process | negative regulation of amino acid transport |
GO_0015820 | Biological process | L-leucine transport |
GO_0015818 | Biological process | isoleucine transport |
GO_0015804 | Biological process | neutral amino acid transport |
GO_1902475 | Biological process | L-alpha-amino acid transmembrane transport |
GO_0006865 | Biological process | amino acid transport |
GO_1905533 | Biological process | negative regulation of L-leucine import across plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0015188 | Molecular function | L-isoleucine transmembrane transporter activity |
GO_0015171 | Molecular function | amino acid transmembrane transporter activity |
GO_0015179 | Molecular function | L-amino acid transmembrane transporter activity |
GO_0015191 | Molecular function | L-methionine transmembrane transporter activity |
GO_0015175 | Molecular function | neutral L-amino acid transmembrane transporter activity |
GO_0015192 | Molecular function | L-phenylalanine transmembrane transporter activity |
GO_0005515 | Molecular function | protein binding |
GO_0015190 | Molecular function | L-leucine transmembrane transporter activity |
Gene name | SLC43A2 |
Protein name | SLC43A2 protein Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2) Large neutral amino acids transporter small subunit 4 (Solute carrier family 43 member 2) |
Synonyms | PP7664 LAT4 |
Description | FUNCTION: Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine . The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent . . |
Accessions | ENST00000382147.8 [Q8N370-4] ENST00000412517.3 [Q8N370-4] I3L3E3 I3L4J2 ENST00000571376.1 ENST00000301335.10 [Q8N370-1] I3L4V3 ENST00000631603.1 ENST00000634102.1 [Q8N370-1] ENST00000633255.1 ENST00000613070.4 [Q8N370-3] ENST00000572801.5 ENST00000612931.4 [Q8N370-3] ENST00000633994.1 ENST00000576721.5 Q8WUU1 ENST00000571650.5 [Q8N370-3] Q8N370 |