SLC39A2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SLC39A2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC39A2 at tissue level.

III. Associated gene sets

GO_0030216Biological processkeratinocyte differentiation
GO_0071577Biological processzinc ion transmembrane transport
GO_0070574Biological processcadmium ion transmembrane transport
GO_0006829Biological processzinc ion transport
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0046873Molecular functionmetal ion transmembrane transporter activity
GO_0005385Molecular functionzinc ion transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC39A2
Protein nameZinc transporter ZIP2 (6A1) (Eti-1) (Solute carrier family 39 member 2) (Zrt- and Irt-like protein 2) (ZIP-2) (hZIP2)
SynonymsZIP2
DescriptionFUNCTION: Transporter for the divalent cation Zn(2+) . Mediates the influx of Zn(2+) into cells from extracellular space. The Zn(2+) uniporter activity is independent of H(+)-driving force, but is modulated by extracellular pH and membrane potential. Transports also other divalent cations Zn(2+), Cd2(+), Cu2(+), Co2(+) in the order of decreasing affinity, respectively . In the skin, aids in the differentiation of keratinocytes in the epidermis (By similarity). .

AccessionsQ9NP94
ENST00000554422.5 [Q9NP94-2]
ENST00000298681.5 [Q9NP94-1]