SLC39A12 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC39A12 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0030003Biological processintracellular monoatomic cation homeostasis
GO_0010975Biological processregulation of neuron projection development
GO_0071578Biological processzinc ion import across plasma membrane
GO_0036293Biological processresponse to decreased oxygen levels
GO_1990138Biological processneuron projection extension
GO_0001841Biological processneural tube formation
GO_0015701Biological processbicarbonate transport
GO_1903672Biological processpositive regulation of sprouting angiogenesis
GO_0031113Biological processregulation of microtubule polymerization
GO_1903561Cellular componentextracellular vesicle
GO_0005886Cellular componentplasma membrane
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005385Molecular functionzinc ion transmembrane transporter activity
GO_0140410Molecular functionmonoatomic cation:bicarbonate symporter activity

IV. Literature review

[source]
Gene nameSLC39A12
Protein nameZinc transporter ZIP12 (LIV-1 subfamily of ZIP zinc transporter 8) (LZT-Hs8) (Solute carrier family 39 member 12) (Zrt- and Irt-like protein 12) (ZIP-12)
SynonymsZIP12
DescriptionFUNCTION: Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane. The transport activity is temperature dependent. May play a role in neurulation and neurite extension. May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis. .

AccessionsENST00000377369.7 [Q504Y0-1]
ENST00000377371.3 [Q504Y0-4]
ENST00000539911.5 [Q504Y0-5]
Q504Y0
ENST00000377374.8 [Q504Y0-3]