Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 11 studies | 32% ± 15% | |
| retinal pigment epithelial cell | 5 studies | 46% ± 13% | |
| Mueller cell | 3 studies | 26% ± 3% |
Insufficient scRNA-seq data for expression of SLC39A12 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 85% | 1104.02 | 2249 / 2642 | 88% | 10.95 | 620 / 705 |
| eye | 0% | 0 | 0 / 0 | 15% | 0.43 | 12 / 80 |
| breast | 0% | 0.54 | 2 / 459 | 5% | 0.18 | 54 / 1118 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.17 | 1 / 29 |
| thymus | 0% | 0 | 0 / 653 | 2% | 0.10 | 13 / 605 |
| lung | 1% | 1.93 | 7 / 578 | 1% | 0.01 | 7 / 1155 |
| adrenal gland | 0% | 0 | 0 / 258 | 2% | 0.03 | 4 / 230 |
| esophagus | 0% | 0 | 0 / 1445 | 1% | 0.05 | 2 / 183 |
| liver | 1% | 0.96 | 2 / 226 | 0% | 0 | 0 / 406 |
| uterus | 0% | 0 | 0 / 170 | 1% | 0.01 | 4 / 459 |
| skin | 0% | 0 | 0 / 1809 | 1% | 0.01 | 3 / 472 |
| adipose | 1% | 0.62 | 7 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 0% | 0 | 0 / 359 | 0% | 0.00 | 1 / 286 |
| pancreas | 0% | 0.30 | 1 / 328 | 0% | 0 | 0 / 178 |
| heart | 0% | 0.26 | 2 / 861 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0.00 | 1 / 504 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.01 | 1 / 901 |
| intestine | 0% | 0.11 | 1 / 966 | 0% | 0 | 0 / 527 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0 | 0 / 502 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0030003 | Biological process | intracellular monoatomic cation homeostasis |
| GO_0010975 | Biological process | regulation of neuron projection development |
| GO_0071578 | Biological process | zinc ion import across plasma membrane |
| GO_0036293 | Biological process | response to decreased oxygen levels |
| GO_1990138 | Biological process | neuron projection extension |
| GO_0001841 | Biological process | neural tube formation |
| GO_0015701 | Biological process | bicarbonate transport |
| GO_1903672 | Biological process | positive regulation of sprouting angiogenesis |
| GO_0031113 | Biological process | regulation of microtubule polymerization |
| GO_1903561 | Cellular component | extracellular vesicle |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005385 | Molecular function | zinc ion transmembrane transporter activity |
| GO_0140410 | Molecular function | monoatomic cation:bicarbonate symporter activity |
| Gene name | SLC39A12 |
| Protein name | Zinc transporter ZIP12 (LIV-1 subfamily of ZIP zinc transporter 8) (LZT-Hs8) (Solute carrier family 39 member 12) (Zrt- and Irt-like protein 12) (ZIP-12) |
| Synonyms | ZIP12 |
| Description | FUNCTION: Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane. The transport activity is temperature dependent. May play a role in neurulation and neurite extension. May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis. . |
| Accessions | ENST00000377369.7 [Q504Y0-1] ENST00000377371.3 [Q504Y0-4] ENST00000539911.5 [Q504Y0-5] Q504Y0 ENST00000377374.8 [Q504Y0-3] |