SLC38A4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1903826Biological processL-arginine transmembrane transport
GO_0006865Biological processamino acid transport
GO_0015804Biological processneutral amino acid transport
GO_0035725Biological processsodium ion transmembrane transport
GO_1904273Biological processL-alanine import across plasma membrane
GO_0003333Biological processamino acid transmembrane transport
GO_0005886Cellular componentplasma membrane
GO_0031528Cellular componentmicrovillus membrane
GO_0061459Molecular functionL-arginine transmembrane transporter activity
GO_0005283Molecular functionamino acid:sodium symporter activity
GO_0015171Molecular functionamino acid transmembrane transporter activity
GO_0015655Molecular functionalanine:sodium symporter activity
GO_0015179Molecular functionL-amino acid transmembrane transporter activity
GO_0005515Molecular functionprotein binding
GO_0005295Molecular functionneutral L-amino acid:sodium symporter activity

IV. Literature review

[source]
Gene nameSLC38A4
Protein nameSodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3) (System N amino acid transporter 3)
Solute carrier family 38 member 4
SynonymsNAT3
ATA3
SNAT4
DescriptionFUNCTION: Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane . The transport is electrogenic, pH dependent and partially tolerates substitution of Na(+) by Li(+) . Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L-proline and L-glutamine and L-methionine . .

AccessionsQ969I6
ENST00000547477.5
H0YHZ8
ENST00000266579.9
F8VRD9
ENST00000447411.5
ENST00000550670.1
ENST00000546940.1
F8VQY9