SLC37A3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0035435Biological processphosphate ion transmembrane transport
GO_0006855Biological processxenobiotic transmembrane transport
GO_0015760Biological processglucose-6-phosphate transport
GO_0005765Cellular componentlysosomal membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0042910Molecular functionxenobiotic transmembrane transporter activity
GO_0005515Molecular functionprotein binding
GO_0061513Molecular functionglucose 6-phosphate:phosphate antiporter activity

IV. Literature review

[source]
Gene nameSLC37A3
Protein nameSugar phosphate exchanger 3 (Solute carrier family 37 member 3)
Solute carrier family 37 member 3
SynonymsSPX3
DescriptionFUNCTION: Unlike the other SLC37 members, lacks glucose-6-phosphate antiporter activity . In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol . .

AccessionsENST00000491505.1
ENST00000492027.5
H7C4U5
ENST00000491357.5
ENST00000469193.5
ENST00000485861.5
H7C4U0
ENST00000485538.1
ENST00000477571.5
F8WF28
ENST00000469636.1
ENST00000477006.1
Q8NCC5
H7C594
H7C4J3
ENST00000340308.7 [Q8NCC5-3]
C9J4S7
H7C4I4
ENST00000462881.1
H7C5T4
ENST00000464834.5
ENST00000490760.5
ENST00000484416.5
H7C5E7
ENST00000485734.1
ENST00000326232.14 [Q8NCC5-1]
H7C4J2
H7C4J5
ENST00000447932.6 [Q8NCC5-2]
ENST00000498469.5
F8WC97
C9JZ37
H7C4Z5
F8WAR9