SLC31A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015677Biological processcopper ion import
GO_1902311Biological processregulation of copper ion transmembrane transport
GO_0006878Biological processintracellular copper ion homeostasis
GO_0006825Biological processcopper ion transport
GO_0035434Biological processcopper ion transmembrane transport
GO_0031902Cellular componentlate endosome membrane
GO_0005886Cellular componentplasma membrane
GO_0005765Cellular componentlysosomal membrane
GO_0055037Cellular componentrecycling endosome
GO_0005375Molecular functioncopper ion transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC31A2
Protein nameProtein SLC31A2 (Copper transporter 2) (hCTR2) (Solute carrier family 31 member 2)
Solute carrier family 31 member 2
Copper transport protein
SynonymsCTR2
hCG_29184
COPT2
DescriptionFUNCTION: Does not function as a copper(1+) importer in vivo (By similarity). However, in vitro functions as a low-affinity copper(1+) importer . Regulator of SLC31A1 which facilitates the cleavage of the SLC31A1 ecto-domain or which stabilizes the truncated form of SLC31A1 (Truncated CTR1 form), thereby drives the SLC31A1 truncated form-dependent endosomal copper export and modulates the copper and cisplatin accumulation via SLC31A1 (By similarity). .

AccessionsENST00000259392.8
ENST00000374220.3
Q53X94
F2Z3D2
O15432