SLC30A6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071579Biological processregulation of zinc ion transport
GO_1904257Biological processzinc ion import into Golgi lumen
GO_0006829Biological processzinc ion transport
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0005794Cellular componentGolgi apparatus
GO_0005385Molecular functionzinc ion transmembrane transporter activity
GO_0140826Molecular functionzinc:proton antiporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC30A6
Protein nameSolute carrier family 30 (Zinc transporter), member 6, isoform CRA_b (Solute carrier family 30 member 6)
Solute carrier family 30 (Zinc transporter), member 6, isoform CRA_c (cDNA FLJ39353 fis, clone PEBLM2002432, highly similar to Homo sapiens solute carrier family 30 (zinc transporter), member 6 (SLC30A6), mRNA) (cDNA FLJ45816 fis, clone NT2RP7019682, highly similar to Homo sapiens solute carrier family 30 (zinc transporter), member 6 (SLC30A6), mRNA)
Solute carrier family 30 member 6
Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6)
SynonymshCG_23082
ZNT6
DescriptionFUNCTION: Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway . As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis . .

AccessionsENST00000406369.2
F8WEL5
ENST00000357055.7 [Q6NXT4-4]
C9JZR9
Q6NXT4
B3KU87
ENST00000454324.5
ENST00000440718.5
F8WCU3
ENST00000379343.6 [Q6NXT4-2]
ENST00000449777.5
ENST00000457724.2
F8WD78
ENST00000435660.5 [Q6NXT4-3]
ENST00000282587.9 [Q6NXT4-1]
B5MCR8