SLC30A2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC30A2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	1420.73	653 / 653	83%	55.62	502 / 605
pancreas	100%	7361.72	328 / 328	66%	13.42	117 / 178
kidney	98%	2223.71	87 / 89	35%	4.24	316 / 901
bladder	71%	63.95	15 / 21	46%	11.98	231 / 504
adrenal gland	86%	148.41	222 / 258	18%	5.22	42 / 230
ureter	0%	0	0 / 0	100%	30.91	1 / 1
eye	0%	0	0 / 0	96%	12.60	77 / 80
muscle	92%	296.51	736 / 803	0%	0	0 / 0
skin	66%	64.94	1192 / 1809	25%	2.00	117 / 472
heart	81%	288.89	695 / 861	0%	0	0 / 0
stomach	20%	11.50	72 / 359	34%	3.17	98 / 286
ovary	1%	0.17	1 / 180	50%	5.18	215 / 430
breast	27%	64.46	126 / 459	23%	2.08	255 / 1118
intestine	11%	14.81	103 / 966	32%	2.99	169 / 527
prostate	33%	27.51	80 / 245	6%	0.36	30 / 502
uterus	15%	11.83	26 / 170	22%	3.27	100 / 459
liver	7%	2.91	15 / 226	19%	3.60	77 / 406
esophagus	6%	3.10	80 / 1445	8%	0.53	15 / 183
lung	6%	3.46	35 / 578	7%	0.63	85 / 1155
adipose	9%	9.83	112 / 1204	0%	0	0 / 0
brain	5%	3.56	119 / 2642	0%	0	0 / 705
blood vessel	2%	2.89	22 / 1335	0%	0	0 / 0
peripheral blood	0%	0.11	3 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45

GO_0071577	Biological process	zinc ion transmembrane transport
GO_0062111	Biological process	zinc ion import into organelle
GO_0140915	Biological process	zinc ion import into zymogen granule
GO_0006882	Biological process	intracellular zinc ion homeostasis
GO_0140917	Biological process	zinc ion import into mitochondrion
GO_0010043	Biological process	response to zinc ion
GO_0140916	Biological process	zinc ion import into lysosome
GO_0005886	Cellular component	plasma membrane
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0042589	Cellular component	zymogen granule membrane
GO_0005770	Cellular component	late endosome
GO_0005737	Cellular component	cytoplasm
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0010008	Cellular component	endosome membrane
GO_0030658	Cellular component	transport vesicle membrane
GO_0005765	Cellular component	lysosomal membrane
GO_0005385	Molecular function	zinc ion transmembrane transporter activity
GO_0140826	Molecular function	zinc:proton antiporter activity
GO_0042802	Molecular function	identical protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding

Gene name	SLC30A2
Protein name	Proton-coupled zinc antiporter SLC30A2 (Solute carrier family 30 member 2) (Zinc transporter 2) (ZnT-2)
Synonyms	ZNT2
Description	FUNCTION: [Isoform 1]: Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity . Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells . By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution . .; FUNCTION: [Isoform 2]: Electroneutral proton-coupled antiporter mediating the efflux of zinc ions through the plasma membrane. .
Accessions	Q9BRI3 ENST00000374276.4 [Q9BRI3-2] ENST00000374278.7 [Q9BRI3-1]

SLC30A2 report