SLC2A5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC2A5 at tissue level.

III. Associated gene sets

GO_1990539Biological processfructose import across plasma membrane
GO_0009750Biological processresponse to fructose
GO_0106001Biological processintestinal hexose absorption
GO_0005975Biological processcarbohydrate metabolic process
GO_1904659Biological processglucose transmembrane transport
GO_0003044Biological processregulation of systemic arterial blood pressure mediated by a chemical signal
GO_0071332Biological processcellular response to fructose stimulus
GO_0015755Biological processfructose transmembrane transport
GO_0016324Cellular componentapical plasma membrane
GO_0042383Cellular componentsarcolemma
GO_0070062Cellular componentextracellular exosome
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0005353Molecular functionfructose transmembrane transporter activity
GO_0070061Molecular functionfructose binding
GO_0005355Molecular functionglucose transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC2A5
Protein nameAlternative protein SLC2A5
Solute carrier family 2, facilitated glucose transporter member 5 (Fructose transporter) (Glucose transporter type 5, small intestine) (GLUT-5)
Solute carrier family 2 member 5
Solute carrier family 2, facilitated glucose transporter member 5 (Fructose transporter) (Glucose transporter type 5, small intestine)
SynonymsGLUT5
DescriptionFUNCTION: Functions as a fructose transporter that has only low activity with other monosaccharides . Can mediate the uptake of 2-deoxyglucose, but with low efficiency . Essential for fructose uptake in the small intestine (By similarity). Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (By similarity). Required for the development of high blood pressure in response to high dietary fructose intake (By similarity). .

AccessionsL8E9T0
ENST00000464985.5
ENST00000486632.5
ENST00000487835.5
ENST00000484798.5
K7EJZ0
ENST00000479813.5
ENST00000377424.9 [P22732-1]
K7EQI3
ENST00000377414.7 [P22732-2]
P22732
ENST00000474145.5
ENST00000473209.1
K7EIT1
K7EJR1