I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 5 studies | 23% ± 4% | |
| endothelial cell | 4 studies | 32% ± 18% | |
| GABAergic neuron | 3 studies | 44% ± 5% | |
| glutamatergic neuron | 3 studies | 43% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 5 studies | 23% ± 4% | |
| endothelial cell | 4 studies | 32% ± 18% | |
| GABAergic neuron | 3 studies | 44% ± 5% | |
| glutamatergic neuron | 3 studies | 43% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 33% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 81% | 959.55 | 145 / 180 | 80% | 7.93 | 344 / 430 |
| thymus | 44% | 225.68 | 287 / 653 | 80% | 73.11 | 486 / 605 |
| adrenal gland | 95% | 1823.67 | 244 / 258 | 20% | 5.33 | 45 / 230 |
| prostate | 53% | 181.14 | 130 / 245 | 60% | 4.47 | 302 / 502 |
| esophagus | 94% | 1245.18 | 1360 / 1445 | 17% | 1.51 | 31 / 183 |
| heart | 93% | 1519.23 | 803 / 861 | 0% | 0 | 0 / 0 |
| breast | 51% | 202.80 | 232 / 459 | 36% | 3.48 | 401 / 1118 |
| brain | 26% | 117.00 | 677 / 2642 | 28% | 1.68 | 198 / 705 |
| bladder | 38% | 146.19 | 8 / 21 | 10% | 1.07 | 52 / 504 |
| uterus | 29% | 109.28 | 50 / 170 | 18% | 1.70 | 84 / 459 |
| skin | 24% | 100.80 | 428 / 1809 | 2% | 0.27 | 10 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 18% | 0.78 | 8 / 45 |
| intestine | 15% | 34.81 | 147 / 966 | 2% | 0.11 | 11 / 527 |
| lung | 5% | 12.18 | 30 / 578 | 6% | 0.72 | 71 / 1155 |
| pancreas | 0% | 0 | 0 / 328 | 4% | 0.18 | 7 / 178 |
| stomach | 1% | 1.93 | 4 / 359 | 2% | 0.38 | 7 / 286 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.19 | 2 / 80 |
| adipose | 2% | 7.59 | 27 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 2% | 7.63 | 26 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 1% | 1.49 | 6 / 803 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.03 | 5 / 901 |
| liver | 0% | 0 | 0 / 226 | 0% | 0.01 | 1 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0044539 | Biological process | long-chain fatty acid import into cell |
| GO_0001676 | Biological process | long-chain fatty acid metabolic process |
| GO_0000038 | Biological process | very long-chain fatty acid metabolic process |
| GO_0015909 | Biological process | long-chain fatty acid transport |
| GO_0042383 | Cellular component | sarcolemma |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_1901480 | Molecular function | oleate transmembrane transporter activity |
| GO_0047676 | Molecular function | arachidonate-CoA ligase activity |
| GO_0004467 | Molecular function | long-chain fatty acid-CoA ligase activity |
| GO_0005324 | Molecular function | long-chain fatty acid transmembrane transporter activity |
| GO_0015245 | Molecular function | fatty acid transmembrane transporter activity |
| GO_0000166 | Molecular function | nucleotide binding |
| GO_0031957 | Molecular function | very long-chain fatty acid-CoA ligase activity |
| Gene name | SLC27A6 |
| Protein name | Long-chain-fatty-acid--CoA ligase Long-chain fatty acid transport protein 6 (FATP-6) (Fatty acid transport protein 6) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 6) (Very long-chain acyl-CoA synthetase homolog 1) (VLCSH1) (hVLCS-H1) (EC 6.2.1.-) |
| Synonyms | FACVL2 ACSVL2 FATP6 |
| Description | FUNCTION: Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane . Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (By similarity). Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation such as the heart . . |
| Accessions | ENST00000395266.5 ENST00000262462.9 D6RAJ2 ENST00000508645.5 ENST00000506176.1 Q9Y2P4 |
