SLC25A46 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0055091Biological processphospholipid homeostasis
GO_0000266Biological processmitochondrial fission
GO_0061564Biological processaxon development
GO_0021702Biological processcerebellar Purkinje cell differentiation
GO_0090149Biological processmitochondrial membrane fission
GO_0006839Biological processmitochondrial transport
GO_0051649Biological processestablishment of localization in cell
GO_0022011Biological processmyelination in peripheral nervous system
GO_0065003Biological processprotein-containing complex assembly
GO_0048936Biological processperipheral nervous system neuron axonogenesis
GO_0021554Biological processoptic nerve development
GO_0042407Biological processcristae formation
GO_0031987Biological processlocomotion involved in locomotory behavior
GO_0008535Biological processrespiratory chain complex IV assembly
GO_0007416Biological processsynapse assembly
GO_0016358Biological processdendrite development
GO_0005739Cellular componentmitochondrion
GO_0005741Cellular componentmitochondrial outer membrane
GO_0044877Molecular functionprotein-containing complex binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC25A46
Protein nameMitochondrial outer membrane protein SLC25A46 (Solute carrier family 25 member 46)
Solute carrier family 25 member 46
Solute carrier family 25 member 46 (cDNA FLJ58689)
SynonymsTB1
DescriptionFUNCTION: Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization . May regulate the assembly of the MICOS (mitochondrial contact site and cristae organizing system) complex which is essential to the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane . Through its interaction with the EMC (endoplasmic reticulum membrane protein complex), could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission . .

AccessionsQ96AG3
ENST00000513807.5
ENST00000447245.6 [Q96AG3-3]
ENST00000504098.1 [Q96AG3-2]
B7Z6C8
ENST00000355943.8 [Q96AG3-1]
ENST00000509432.1
E7EVY2